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Gene Information
Gene ID:284186
Symbol:TMEM105
Full Name:transmembrane protein 105
Alias:FLJ38792
Organism:Homo sapiens (Human)
Chromosome:17
Genetic Location:17q25.3
Physical Location:76899668-76919068 on NC_000017.9, complement
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Linkage Dataset
MarkerLODP valueLocation (bp)
D17S928  77846128
Region:75846128-78774742
Phenotype:Alcoholism phenotype along with age, gender, and P300 or constraint
Name:15211641
Method:Linkage
Publication:Hill et al. Am J Med Genet B Neuropsychiatr Genet. (2004) A genome wide search for alcoholism susceptibility genes. PubMed
Summary:A total of 360 markers for 22 autosomes were spaced at an average distance of 9.4cMand genotyping performed for 330 members of these multiplex families. Extensive clinical data, personality variation, and event-related potential characteristics were available for reducing heterogeneity and detecting robust linkage signals. Multipoint linkage analysis using different analytic strategies give strong support for loci on chromosomes 1, 2, 6, 7, 10, 12, 14, 16, and 17. Thirty five markers with LOD score >2.0 at baseline using the binary alcoholism phenotype along with age, gender, and P300 or constraint (Table III). Here we listed the genes between two near markers or genes near a separate marker (within 2Mb).
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_178520.2NP_848615.1NC_000017.9 range: 76899668..76919068, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0016020membraneCellular ComponentIEA
GO:0016021integral to membraneCellular ComponentIEA
Other Database Cross Links
NCBI Entrez Gene:284186
HGNC:26794
Ensembl:ENSG00000185332
MIM:
HPRD:08247
HuGE Navigator:284186
dbSNP:TMEM105
GeneCard:TMEM105
AceView:TMEM105