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Gene Information
Gene ID:285555
Symbol:C4orf37
Full Name:chromosome 4 open reading frame 37
Alias:MGC46496
Organism:Homo sapiens (Human)
Chromosome:4
Genetic Location:4q22.3-q23
Physical Location:98699057-99283413 on NC_000004.10, complement
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Linkage Dataset
MarkerLODP valueLocation (bp)
D4S4232.610.000392691777
D4S4273.530.00003121646580
Region:92691777-121646580
Phenotype:ADSX (number of DSM-IV AD symptoms)
Name:16534506
Method:Linkage
Publication:Prescott et al. Mol Psychiatry. (2006) Genomewide linkage study in the Irish affected sib pair study of alcohol dependence: evidence for a susceptibility region for symptoms of alcohol dependence on chromosome 4. PubMed
Summary:We conducted a genome scan in the Irish Affected Sib Pair Study of Alcohol Dependence (IASPSAD). A 4 cM genome scan was conducted using 474 families of which most (96%) were comprised by affected sib pairs. Nonparametric and quantitative linkage analyses were conducted using DSM-IV alcohol dependence (AD) and number of DSM-IV AD symptoms (ADSX). Quantitative results indicate strong linkage for number of AD criteria to a broad region of chromosome 4, ranging from 4q22 to 4q32 (peak multipoint LOD=4.59, P=2.1 x 10(-6), at D4S1611). We got the gene list in the region between two markers D4S423 and D4S427 as markers between (included) these two markers have LOD scores >2 with P value <0.0003.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_174952.1NP_777612.1NC_000004.10 range: 98699057..99283413, complement
Other Database Cross Links
NCBI Entrez Gene:285555
HGNC:28712
Ensembl:ENSG00000163116
MIM:
HPRD:14650
HuGE Navigator:285555
dbSNP:C4orf37
GeneCard:C4orf37
AceView:C4orf37