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Gene Information
Gene ID:285704
Symbol:RGMB
Full Name:RGM domain family, member B
Alias:DRAGON|FLJ90406|MGC86970
Organism:Homo sapiens (Human)
Chromosome:5
Genetic Location:5q21.1
Physical Location:98132899-98160097 on NC_000005.8
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Linkage Dataset
MarkerLODP valueLocation (bp)
D5S644  95838450
Region:95838450-103990852
Phenotype:Alcoholism phenotype along with age, gender, and P300 or constraint
Name:15211641
Method:Linkage
Publication:Hill et al. Am J Med Genet B Neuropsychiatr Genet. (2004) A genome wide search for alcoholism susceptibility genes. PubMed
Summary:A total of 360 markers for 22 autosomes were spaced at an average distance of 9.4cMand genotyping performed for 330 members of these multiplex families. Extensive clinical data, personality variation, and event-related potential characteristics were available for reducing heterogeneity and detecting robust linkage signals. Multipoint linkage analysis using different analytic strategies give strong support for loci on chromosomes 1, 2, 6, 7, 10, 12, 14, 16, and 17. Thirty five markers with LOD score >2.0 at baseline using the binary alcoholism phenotype along with age, gender, and P300 or constraint (Table III). Here we listed the genes between two near markers or genes near a separate marker (within 2Mb).
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_001012761.1NP_001012779.1NC_000005.8 range: 98132899..98160097
NM_173670.2NP_775941.1NC_000005.8 range: 98132899..98160097
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005793ER-Golgi intermediate compartmentCellular ComponentISS
GO:0005886plasma membraneCellular ComponentIEA
GO:0046658anchored to plasma membraneCellular ComponentISS
GO:0042802identical protein bindingMolecular FunctionISS
GO:0007155cell adhesionBiological ProcessISS
GO:0007165signal transductionBiological ProcessISS
GO:0030509BMP signaling pathwayBiological ProcessISS
GO:0045941positive regulation of transcriptionBiological ProcessISS
Other Database Cross Links
NCBI Entrez Gene:285704
HGNC:26896
Ensembl:ENSG00000174136
MIM:
HPRD:15243
HuGE Navigator:285704
dbSNP:RGMB
GeneCard:RGMB
AceView:RGMB