ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

GPT

Full Name:

glutamic-pyruvate transaminase (alanine aminotransferase)

Alias:

AAT1|ALT1|GPT1

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

8q24.3

Physical Location:

145700230-145703356 on NC_000008.9

Gene Type:

protein-coding

Orthologs:

This gene has Mouse: 76282 ortholog(s) in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

GPT

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_005309.2	NP_005300.1	NC_000008.9 range: 145700230..145703356

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005625	soluble fraction	Cellular Component	NR
GO:0005737	cytoplasm	Cellular Component	NAS
GO:0005829	cytosol	Cellular Component	EXP (9119391)
GO:0004021	alanine transaminase activity	Molecular Function	EXP (9119391)
GO:0016847	1-aminocyclopropane-1-carboxylate synthase activity	Molecular Function	IEA
GO:0030170	pyridoxal phosphate binding	Molecular Function	IEA
GO:0004021	alanine transaminase activity	Molecular Function	NAS (1931970)
GO:0006807	nitrogen compound metabolic process	Biological Process	NAS
GO:0009058	biosynthetic process	Biological Process	IEA
GO:0006094	gluconeogenesis	Biological Process	NAS