Gene Information |
Gene ID: | | 2899 |
Symbol: | | GRIK3 |
Full Name: | | glutamate receptor, ionotropic, kainate 3 |
Alias: | | EAA5|GLR7|GLUR7|GluR7a |
Organism: | | Homo sapiens (Human) |
Chromosome: | | 1 |
Genetic Location: | | 1p34-p33 |
Physical Location: | | 37039200-37272430 on NC_000001.9, complement |
Gene Type: | | protein-coding |
Orthologs: | | This gene has no orthologs in other dataset(s). |
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Gene in Ethanol Study Datasets |
Gene Information | | Dataset Information | Name: | | Literature Search | Method: | | Literature search | Summary: | | We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive. |
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Gene Information | Original ID | No. of Publications | Phenotype | |
GRIK3 | 1 | Alcohol-Induced Disorders | GRIK3 | 1 | Alcohol-Induced Disorders Nervous System | GRIK3 | 2 | Alcoholism | GRIK3 | 2 | Alcohol-Related Disorders | GRIK3 | 1 | Alcohol Withdrawal Delirium | GRIK3 | 1 | Alcohol Withdrawal Seizures |
| HuGE Navigator Dataset | Name: | | HuGE Navigator | Method: | | Literature data mining | Publication: | | Wei Yu, Melinda Clyne, Anja Wulf, Ajay Yesupriya, Marta Gwinn and Muin J. Khoury. Phenopedia. HuGE Navigator. Available at: http://www.hugenavigator.net/HuGENavigator/startPagePhenoPedia.do. Accessed [Jun. 10, 2008]. | Summary: | | HuGE Navigator Phenopedia provides a disease-centered view of genetic association studies summarized in the online Human Genome Epidemiology (HuGE) encyclopedia. We extracted genes associated to 9 Alcohol-related diseases (Alcohol Amnestic Disorder; Alcohol Withdrawal Delirium; Alcohol Withdrawal Seizures; Alcohol-Induced Disorders; Alcohol-Induced Disorders, Nervous System; Alcohol-Related Disorders; Alcoholic Intoxication; Alcoholic Neuropathy; Alcoholism) from HuGE Navigator Phenopedia. |
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Gene Refseq Sequence Annotation |
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Gene Ontology (GO) Annotation |
GO ID | GO Term | Category | Evidence (PubMed) | |
GO:0045211 | postsynaptic membrane | Cellular Component | IEA | |
GO:0045202 | synapse | Cellular Component | IEA | |
GO:0030054 | cell junction | Cellular Component | IEA | |
GO:0016021 | integral to membrane | Cellular Component | IEA | |
GO:0005624 | membrane fraction | Cellular Component | NR | |
GO:0005886 | plasma membrane | Cellular Component | IEA | |
GO:0005887 | integral to plasma membrane | Cellular Component | TAS (7719709) | |
GO:0016020 | membrane | Cellular Component | IEA | |
GO:0015277 | kainate selective glutamate receptor activity | Molecular Function | TAS (7719709) | |
GO:0004872 | receptor activity | Molecular Function | IEA | |
GO:0005234 | extracellular-glutamate-gated ion channel activity | Molecular Function | IEA | |
GO:0005216 | ion channel activity | Molecular Function | IEA | |
GO:0004970 | ionotropic glutamate receptor activity | Molecular Function | IEA | |
GO:0006811 | ion transport | Biological Process | IEA | |
GO:0042391 | regulation of membrane potential | Biological Process | IDA (11124978) | |
GO:0007215 | glutamate signaling pathway | Biological Process | TAS (7719709) | |
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Other Database Cross Links |
NCBI Entrez Gene: | | 2899 |
HGNC: | | 4581 |
Ensembl: | | ENSG00000163873 |
MIM: | | 138243 |
HPRD: | | 00691 |
HuGE Navigator: | | 2899 |
dbSNP: | | GRIK3 |
GeneCard: | | GRIK3 |
AceView: | | GRIK3 |