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Gene Information
Gene ID:2899
Full Name:glutamate receptor, ionotropic, kainate 3
Organism:Homo sapiens (Human)
Genetic Location:1p34-p33
Physical Location:37039200-37272430 on NC_000001.9, complement
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:GRIK3
Dataset Information
Name:Literature Search
Method:Literature search
Summary:We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.
Gene Information
Original IDNo. of PublicationsPhenotype
GRIK31Alcohol-Induced Disorders
GRIK31Alcohol-Induced Disorders Nervous System
GRIK32Alcohol-Related Disorders
GRIK31Alcohol Withdrawal Delirium
GRIK31Alcohol Withdrawal Seizures
HuGE Navigator Dataset
Name:HuGE Navigator
Method:Literature data mining
Publication:Wei Yu, Melinda Clyne, Anja Wulf, Ajay Yesupriya, Marta Gwinn and Muin J. Khoury. Phenopedia. HuGE Navigator. Available at: http://www.hugenavigator.net/HuGENavigator/startPagePhenoPedia.do. Accessed [Jun. 10, 2008].
Summary:HuGE Navigator Phenopedia provides a disease-centered view of genetic association studies summarized in the online Human Genome Epidemiology (HuGE) encyclopedia. We extracted genes associated to 9 Alcohol-related diseases (Alcohol Amnestic Disorder; Alcohol Withdrawal Delirium; Alcohol Withdrawal Seizures; Alcohol-Induced Disorders; Alcohol-Induced Disorders, Nervous System; Alcohol-Related Disorders; Alcoholic Intoxication; Alcoholic Neuropathy; Alcoholism) from HuGE Navigator Phenopedia.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_000831.3NP_000822.2NC_000001.9 range: 37039200..37272430, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0045211postsynaptic membraneCellular ComponentIEA
GO:0045202synapseCellular ComponentIEA
GO:0030054cell junctionCellular ComponentIEA
GO:0016021integral to membraneCellular ComponentIEA
GO:0005624membrane fractionCellular ComponentNR
GO:0005886plasma membraneCellular ComponentIEA
GO:0005887integral to plasma membraneCellular ComponentTAS (7719709)
GO:0016020membraneCellular ComponentIEA
GO:0015277kainate selective glutamate receptor activityMolecular FunctionTAS (7719709)
GO:0004872receptor activityMolecular FunctionIEA
GO:0005234extracellular-glutamate-gated ion channel activityMolecular FunctionIEA
GO:0005216ion channel activityMolecular FunctionIEA
GO:0004970ionotropic glutamate receptor activityMolecular FunctionIEA
GO:0006811ion transportBiological ProcessIEA
GO:0042391regulation of membrane potentialBiological ProcessIDA (11124978)
GO:0007215glutamate signaling pathwayBiological ProcessTAS (7719709)
Other Database Cross Links
NCBI Entrez Gene:2899
HuGE Navigator:2899