ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

ANPEP

Full Name:

alanyl (membrane) aminopeptidase (aminopeptidase N, aminopeptidase M, microsomal aminopeptidase, CD13, p150)

Alias:

APN|CD13|LAP1|PEPN|gp150

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

15q25-q26

Physical Location:

88129129-88159075 on NC_000015.8, complement

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID	No. of Publications	Phenotype
ANPEP	1	Alcoholism

HuGE Navigator Dataset

Name:		HuGE Navigator
Method:		Literature data mining
Publication:		Wei Yu, Melinda Clyne, Anja Wulf, Ajay Yesupriya, Marta Gwinn and Muin J. Khoury. Phenopedia. HuGE Navigator. Available at: http://www.hugenavigator.net/HuGENavigator/startPagePhenoPedia.do. Accessed [Jun. 10, 2008].
Summary:		HuGE Navigator Phenopedia provides a disease-centered view of genetic association studies summarized in the online Human Genome Epidemiology (HuGE) encyclopedia. We extracted genes associated to 9 Alcohol-related diseases (Alcohol Amnestic Disorder; Alcohol Withdrawal Delirium; Alcohol Withdrawal Seizures; Alcohol-Induced Disorders; Alcohol-Induced Disorders, Nervous System; Alcohol-Related Disorders; Alcoholic Intoxication; Alcoholic Neuropathy; Alcoholism) from HuGE Navigator Phenopedia.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_001150.2	NP_001141.2	NC_000015.8 range: 88129129..88159075, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005887	integral to plasma membrane	Cellular Component	TAS (2564851)
GO:0005737	cytoplasm	Cellular Component	IEA
GO:0005793	ER-Golgi intermediate compartment	Cellular Component	IDA (15308636)
GO:0005886	plasma membrane	Cellular Component	IEA
GO:0008270	zinc ion binding	Molecular Function	IEA
GO:0008237	metallopeptidase activity	Molecular Function	TAS (2564851)
GO:0046872	metal ion binding	Molecular Function	IEA
GO:0004872	receptor activity	Molecular Function	TAS (1350662)
GO:0004179	membrane alanyl aminopeptidase activity	Molecular Function	IEA
GO:0004177	aminopeptidase activity	Molecular Function	TAS (10734069)
GO:0006508	proteolysis	Biological Process	IEA
GO:0007275	multicellular organismal development	Biological Process	IEA
GO:0030154	cell differentiation	Biological Process	IEA
GO:0001525	angiogenesis	Biological Process	IEA