| Gene Information |
| Gene ID: | | 2917 |
| Symbol: | | GRM7 |
| Full Name: | | glutamate receptor, metabotropic 7 |
| Alias: | | FLJ40498|GLUR7|GPRC1G|MGLUR7|mGlu7 |
| Organism: | | Homo sapiens (Human) |
| Chromosome: | | 3 |
| Genetic Location: | | 3p26.1-p25.1 |
| Physical Location: | | 6877926-7758216 on NC_000003.10 |
| Gene Type: | | protein-coding |
| Orthologs: | | This gene has no orthologs in other dataset(s). |
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| Gene in Ethanol Study Datasets |
| Gene Information | | | Dataset Information | | Name: | | Literature Search | | Method: | | Literature search | | Summary: | | We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive. |
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| Gene Information | | Original ID | No. of Publications | Phenotype | |
| GRM7 | 1 | Alcohol-Induced Disorders | | GRM7 | 1 | Alcohol-Induced Disorders Nervous System | | GRM7 | 1 | Alcoholism | | GRM7 | 1 | Alcohol-Related Disorders | | GRM7 | 1 | Alcohol Withdrawal Delirium | | GRM7 | 1 | Alcohol Withdrawal Seizures |
| | HuGE Navigator Dataset | | Name: | | HuGE Navigator | | Method: | | Literature data mining | | Publication: | | Wei Yu, Melinda Clyne, Anja Wulf, Ajay Yesupriya, Marta Gwinn and Muin J. Khoury. Phenopedia. HuGE Navigator. Available at: http://www.hugenavigator.net/HuGENavigator/startPagePhenoPedia.do. Accessed [Jun. 10, 2008]. | | Summary: | | HuGE Navigator Phenopedia provides a disease-centered view of genetic association studies summarized in the online Human Genome Epidemiology (HuGE) encyclopedia. We extracted genes associated to 9 Alcohol-related diseases (Alcohol Amnestic Disorder; Alcohol Withdrawal Delirium; Alcohol Withdrawal Seizures; Alcohol-Induced Disorders; Alcohol-Induced Disorders, Nervous System; Alcohol-Related Disorders; Alcoholic Intoxication; Alcoholic Neuropathy; Alcoholism) from HuGE Navigator Phenopedia. |
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| Gene Refseq Sequence Annotation |
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| Gene Ontology (GO) Annotation |
| GO ID | GO Term | Category | Evidence (PubMed) | |
| GO:0005886 | plasma membrane | Cellular Component | IEA | |
| GO:0005887 | integral to plasma membrane | Cellular Component | TAS (9473604) | |
| GO:0048787 | presynaptic active zone membrane | Cellular Component | TAS (12052533) | |
| GO:0045211 | postsynaptic membrane | Cellular Component | TAS (12052533) | |
| GO:0004872 | receptor activity | Molecular Function | IEA | |
| GO:0030165 | PDZ domain binding | Molecular Function | TAS (12052533) | |
| GO:0008067 | metabotropic glutamate, GABA-B-like receptor activity | Molecular Function | TAS (9473604) | |
| GO:0042596 | fear response | Biological Process | TAS (12052533) | |
| GO:0007608 | sensory perception of smell | Biological Process | IEA | |
| GO:0007268 | synaptic transmission | Biological Process | TAS (9473604) | |
| GO:0007194 | negative regulation of adenylate cyclase activity | Biological Process | TAS (9473604) | |
| GO:0007186 | G-protein coupled receptor protein signaling pathway | Biological Process | IEA | |
| GO:0007165 | signal transduction | Biological Process | IEA | |
| GO:0050896 | response to stimulus | Biological Process | IEA | |
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| Other Database Cross Links |
| NCBI Entrez Gene: | | 2917 |
| HGNC: | | 4599 |
| Ensembl: | | ENSG00000196277 |
| MIM: | | 604101 |
| HPRD: | | 04979 |
| HuGE Navigator: | | 2917 |
| dbSNP: | | GRM7 |
| GeneCard: | | GRM7 |
| AceView: | | GRM7 |
