Gene Information |
Gene ID: | | 2918 |
Symbol: | | GRM8 |
Full Name: | | glutamate receptor, metabotropic 8 |
Alias: | | FLJ41058|GLUR8|GPRC1H|MGC126724|MGLUR8|mGlu8 |
Organism: | | Homo sapiens (Human) |
Chromosome: | | 7 |
Genetic Location: | | 7q31.3-q32.1 |
Physical Location: | | 125865894-126670547 on NC_000007.12, complement |
Gene Type: | | protein-coding |
Orthologs: | | This gene has no orthologs in other dataset(s). |
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Gene in Ethanol Study Datasets |
Gene Information | Original ID | No. of Publications | Phenotype | |
GRM8 | 1 | Alcohol-Induced Disorders | GRM8 | 1 | Alcohol-Induced Disorders Nervous System | GRM8 | 1 | Alcoholism | GRM8 | 1 | Alcohol-Related Disorders | GRM8 | 1 | Alcohol Withdrawal Delirium | GRM8 | 1 | Alcohol Withdrawal Seizures |
| HuGE Navigator Dataset | Name: | | HuGE Navigator | Method: | | Literature data mining | Publication: | | Wei Yu, Melinda Clyne, Anja Wulf, Ajay Yesupriya, Marta Gwinn and Muin J. Khoury. Phenopedia. HuGE Navigator. Available at: http://www.hugenavigator.net/HuGENavigator/startPagePhenoPedia.do. Accessed [Jun. 10, 2008]. | Summary: | | HuGE Navigator Phenopedia provides a disease-centered view of genetic association studies summarized in the online Human Genome Epidemiology (HuGE) encyclopedia. We extracted genes associated to 9 Alcohol-related diseases (Alcohol Amnestic Disorder; Alcohol Withdrawal Delirium; Alcohol Withdrawal Seizures; Alcohol-Induced Disorders; Alcohol-Induced Disorders, Nervous System; Alcohol-Related Disorders; Alcoholic Intoxication; Alcoholic Neuropathy; Alcoholism) from HuGE Navigator Phenopedia. |
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Gene Refseq Sequence Annotation |
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Gene Ontology (GO) Annotation |
GO ID | GO Term | Category | Evidence (PubMed) | |
GO:0005886 | plasma membrane | Cellular Component | IEA | |
GO:0005887 | integral to plasma membrane | Cellular Component | TAS (9473604) | |
GO:0016021 | integral to membrane | Cellular Component | IEA | |
GO:0004872 | receptor activity | Molecular Function | IEA | |
GO:0008067 | metabotropic glutamate, GABA-B-like receptor activity | Molecular Function | TAS (9473604) | |
GO:0008067 | metabotropic glutamate, GABA-B-like receptor activity | Molecular Function | IEA | |
GO:0030818 | negative regulation of cAMP biosynthetic process | Biological Process | IDA (11166323) | |
GO:0007608 | sensory perception of smell | Biological Process | IEA | |
GO:0007601 | visual perception | Biological Process | TAS (9473604) | |
GO:0007268 | synaptic transmission | Biological Process | NR | |
GO:0007194 | negative regulation of adenylate cyclase activity | Biological Process | TAS (9473604) | |
GO:0007186 | G-protein coupled receptor protein signaling pathway | Biological Process | IEA | |
GO:0007165 | signal transduction | Biological Process | IEA | |
GO:0050896 | response to stimulus | Biological Process | IEA | |
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Other Database Cross Links |
NCBI Entrez Gene: | | 2918 |
HGNC: | | 4600 |
Ensembl: | | ENSG00000179603 |
MIM: | | 601116 |
HPRD: | | 03071 |
HuGE Navigator: | | 2918 |
dbSNP: | | GRM8 |
GeneCard: | | GRM8 |
AceView: | | GRM8 |