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Gene Information
Gene ID:2918
Symbol:GRM8
Full Name:glutamate receptor, metabotropic 8
Alias:FLJ41058|GLUR8|GPRC1H|MGC126724|MGLUR8|mGlu8
Organism:Homo sapiens (Human)
Chromosome:7
Genetic Location:7q31.3-q32.1
Physical Location:125865894-126670547 on NC_000007.12, complement
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original IDNo. of PublicationsPhenotype
GRM81Alcohol-Induced Disorders
GRM81Alcohol-Induced Disorders Nervous System
GRM81Alcoholism
GRM81Alcohol-Related Disorders
GRM81Alcohol Withdrawal Delirium
GRM81Alcohol Withdrawal Seizures
HuGE Navigator Dataset
Name:HuGE Navigator
Method:Literature data mining
Publication:Wei Yu, Melinda Clyne, Anja Wulf, Ajay Yesupriya, Marta Gwinn and Muin J. Khoury. Phenopedia. HuGE Navigator. Available at: http://www.hugenavigator.net/HuGENavigator/startPagePhenoPedia.do. Accessed [Jun. 10, 2008].
Summary:HuGE Navigator Phenopedia provides a disease-centered view of genetic association studies summarized in the online Human Genome Epidemiology (HuGE) encyclopedia. We extracted genes associated to 9 Alcohol-related diseases (Alcohol Amnestic Disorder; Alcohol Withdrawal Delirium; Alcohol Withdrawal Seizures; Alcohol-Induced Disorders; Alcohol-Induced Disorders, Nervous System; Alcohol-Related Disorders; Alcoholic Intoxication; Alcoholic Neuropathy; Alcoholism) from HuGE Navigator Phenopedia.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_000845.2NP_000836.2NC_000007.12 range: 125865894..126670547, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005886plasma membraneCellular ComponentIEA
GO:0005887integral to plasma membraneCellular ComponentTAS (9473604)
GO:0016021integral to membraneCellular ComponentIEA
GO:0004872receptor activityMolecular FunctionIEA
GO:0008067metabotropic glutamate, GABA-B-like receptor activityMolecular FunctionTAS (9473604)
GO:0008067metabotropic glutamate, GABA-B-like receptor activityMolecular FunctionIEA
GO:0030818negative regulation of cAMP biosynthetic processBiological ProcessIDA (11166323)
GO:0007608sensory perception of smellBiological ProcessIEA
GO:0007601visual perceptionBiological ProcessTAS (9473604)
GO:0007268synaptic transmissionBiological ProcessNR
GO:0007194negative regulation of adenylate cyclase activityBiological ProcessTAS (9473604)
GO:0007186G-protein coupled receptor protein signaling pathwayBiological ProcessIEA
GO:0007165signal transductionBiological ProcessIEA
GO:0050896response to stimulusBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:2918
HGNC:4600
Ensembl:ENSG00000179603
MIM:601116
HPRD:03071
HuGE Navigator:2918
dbSNP:GRM8
GeneCard:GRM8
AceView:GRM8