ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

GSTM1

Full Name:

glutathione S-transferase M1

Alias:

GST1|GSTM1-1|GSTM1a-1a|GSTM1b-1b|GTH4|GTM1|H-B|MGC26563|MU|MU-1

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

1p13.3

Physical Location:

110031964-110037889 on NC_000001.9

Gene Type:

protein-coding

Orthologs:

This gene has Mouse: 14862 ortholog(s) in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

GSTM1

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Information

Original ID	No. of Publications	Phenotype
GSTM1	6	Alcohol-Induced Disorders
GSTM1	1	Alcohol-Induced Disorders Nervous System
GSTM1	6	Alcoholism
GSTM1	9	Alcohol-Related Disorders
GSTM1	1	Alcohol Withdrawal Delirium

HuGE Navigator Dataset

Name:		HuGE Navigator
Method:		Literature data mining
Publication:		Wei Yu, Melinda Clyne, Anja Wulf, Ajay Yesupriya, Marta Gwinn and Muin J. Khoury. Phenopedia. HuGE Navigator. Available at: http://www.hugenavigator.net/HuGENavigator/startPagePhenoPedia.do. Accessed [Jun. 10, 2008].
Summary:		HuGE Navigator Phenopedia provides a disease-centered view of genetic association studies summarized in the online Human Genome Epidemiology (HuGE) encyclopedia. We extracted genes associated to 9 Alcohol-related diseases (Alcohol Amnestic Disorder; Alcohol Withdrawal Delirium; Alcohol Withdrawal Seizures; Alcohol-Induced Disorders; Alcohol-Induced Disorders, Nervous System; Alcohol-Related Disorders; Alcoholic Intoxication; Alcoholic Neuropathy; Alcoholism) from HuGE Navigator Phenopedia.

Gene Refseq Sequence Annotation

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005737	cytoplasm	Cellular Component	IEA
GO:0004364	glutathione transferase activity	Molecular Function	IEA
GO:0004364	glutathione transferase activity	Molecular Function	TAS (8403204)
GO:0016740	transferase activity	Molecular Function	IEA
GO:0008152	metabolic process	Biological Process	IEA