ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Amigo1

Full Name:

adhesion molecule with Ig like domain 1

Alias:

Amigo

Organism:

Rattus norvegicus (Rat)

Chromosome:

Genetic Location:

2q34

Physical Location:

203752631-203754112 on NC_005101.2

Gene Type:

protein-coding

Human Ortholog:

GeneID: 57463 Symbol (Name): AMIGO1 (adhesion molecule with Ig-like domain 1)

Ortholog Status:

The human GeneID 57463 is not in current human dataset.

Gene in Ethanol Study Datasets

Gene Information

Dataset Information

Name:		17517326
Method:		Microarray
Tissue:		Nucleus accumbens, amygdala, frontal cortex, caudate-putamen, and hippocampus
Phenotype:		Alcohol-preferring, alcohol-nonpreferring
Publication:		Kimpel et al. Alcohol. (2007) Functional gene expression differences between inbred alcohol-preferring and -non-preferring rats in five brain regions. PubMed
Summary:		The objective of this study was to determine if there are innate differences in gene expression in selected CNS regions between inbred alcohol-preferring (iP) and -non-preferring (iNP) rats. Gene expression was determined in the nucleus accumbens (ACB), amygdala (AMYG), frontal cortex (FC), caudate-putamen (CPU), and hippocampus (HIPP) of alcohol-naive adult male iP and iNP rats, using Affymetrix Rat Genome U34A microarrays (n = 6/strain). Using Linear Modeling for Microarray Analysis with a false discovery rate threshold of 0.1, there were 16 genes with differential expression in the ACB, 54 in the AMYG, 8 in the FC, 24 in the CPU, and 21 in the HIPP. All the fold change are iP vs. iNP fold change.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_206881.1	NP_996764.1	NC_005101.2 range: 203752631..203754112

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005887	integral to plasma membrane	Cellular Component	NAS
GO:0016021	integral to membrane	Cellular Component	IDA (12629050)
GO:0016020	membrane	Cellular Component	IEA
GO:0005515	protein binding	Molecular Function	IPI
GO:0042552	myelination	Biological Process	IEP
GO:0030154	cell differentiation	Biological Process	IEA
GO:0007413	axonal fasciculation	Biological Process	IDA
GO:0007409	axonogenesis	Biological Process	IDA (12629050)
GO:0007399	nervous system development	Biological Process	IEA
GO:0007275	multicellular organismal development	Biological Process	IEA
GO:0007157	heterophilic cell adhesion	Biological Process	IPI
GO:0007156	homophilic cell adhesion	Biological Process	IPI
GO:0007155	cell adhesion	Biological Process	TAS (12629050)
GO:0007155	cell adhesion	Biological Process	IEA
GO:0050772	positive regulation of axonogenesis	Biological Process	IDA