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Gene Information
Gene ID:29619
Full Name:B-cell translocation gene 2, anti-proliferative
Organism:Rattus norvegicus (Rat)
Physical Location:47026985-47030744 on NC_005112.2, complement
Gene Type:protein-coding
Human Ortholog:GeneID: 7832    Symbol (Name): BTG2 (BTG family, member 2)
Ortholog Status:The human GeneID 7832 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Btg2
Fold Change:1.19
Dataset Information
Tissue:Nucleus accumbens, amygdala, frontal cortex, caudate-putamen, and hippocampus
Phenotype:Alcohol-preferring, alcohol-nonpreferring
Publication:Kimpel et al. Alcohol. (2007) Functional gene expression differences between inbred alcohol-preferring and -non-preferring rats in five brain regions. PubMed
Summary:The objective of this study was to determine if there are innate differences in gene expression in selected CNS regions between inbred alcohol-preferring (iP) and -non-preferring (iNP) rats. Gene expression was determined in the nucleus accumbens (ACB), amygdala (AMYG), frontal cortex (FC), caudate-putamen (CPU), and hippocampus (HIPP) of alcohol-naive adult male iP and iNP rats, using Affymetrix Rat Genome U34A microarrays (n = 6/strain). Using Linear Modeling for Microarray Analysis with a false discovery rate threshold of 0.1, there were 16 genes with differential expression in the ACB, 54 in the AMYG, 8 in the FC, 24 in the CPU, and 21 in the HIPP. All the fold change are iP vs. iNP fold change.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_017259.1NP_058955.1NC_005112.2 range: 47026985..47030744, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005515protein bindingMolecular FunctionIPI
GO:0005515protein bindingMolecular FunctionISS
GO:0045768positive regulation of anti-apoptosisBiological ProcessIMP (12360398)
GO:0043434response to peptide hormone stimulusBiological ProcessIEP (8263025)
GO:0043066negative regulation of apoptosisBiological ProcessIDA
GO:0030182neuron differentiationBiological ProcessIDA
GO:0014070response to organic cyclic substanceBiological ProcessIEP (2005087)
GO:0010243response to organic nitrogenBiological ProcessIEP (2005087)
GO:0010033response to organic substanceBiological ProcessIEP (15084757)
GO:0009952anterior/posterior pattern formationBiological ProcessISS
GO:0009952anterior/posterior pattern formationBiological ProcessIEA
GO:0009612response to mechanical stimulusBiological ProcessIEP (15519684)
GO:0006479protein amino acid methylationBiological ProcessISS
GO:0006479protein amino acid methylationBiological ProcessIEA
GO:0006355regulation of transcription, DNA-dependentBiological ProcessIEA
GO:0006350transcriptionBiological ProcessIEA
GO:0051602response to electrical stimulusBiological ProcessIEP (8879470)
Other Database Cross Links
NCBI Entrez Gene:29619