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Gene Information
Gene ID:29672
Symbol:Psma5
Full Name:proteasome (prosome, macropain) subunit, alpha type 5
Organism:Rattus norvegicus (Rat)
Chromosome:2
Genetic Location:2q34
Physical Location:203825059-203848377 on NC_005101.2
Gene Type:protein-coding
Human Ortholog:GeneID: 5686    Symbol (Name): PSMA5 (proteasome (prosome, macropain) subunit, alpha type, 5)
Ortholog Status:The human GeneID 5686 is not in current human dataset.
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Psma5
Fold Change:1.44
Tissue:Accumbens
Gene Information
Original ID1:Psma5
Fold Change:1.57
Tissue:Amygdala
Gene Information
Original ID1:Psma5
Fold Change:1.78
Tissue:Frontalcortex
Gene Information
Original ID1:Psma5
Fold Change:1.63
Tissue:Caudate-putamen
Dataset Information
Name:17517326
Method:Microarray
Tissue:Nucleus accumbens, amygdala, frontal cortex, caudate-putamen, and hippocampus
Phenotype:Alcohol-preferring, alcohol-nonpreferring
Publication:Kimpel et al. Alcohol. (2007) Functional gene expression differences between inbred alcohol-preferring and -non-preferring rats in five brain regions. PubMed
Summary:The objective of this study was to determine if there are innate differences in gene expression in selected CNS regions between inbred alcohol-preferring (iP) and -non-preferring (iNP) rats. Gene expression was determined in the nucleus accumbens (ACB), amygdala (AMYG), frontal cortex (FC), caudate-putamen (CPU), and hippocampus (HIPP) of alcohol-naive adult male iP and iNP rats, using Affymetrix Rat Genome U34A microarrays (n = 6/strain). Using Linear Modeling for Microarray Analysis with a false discovery rate threshold of 0.1, there were 16 genes with differential expression in the ACB, 54 in the AMYG, 8 in the FC, 24 in the CPU, and 21 in the HIPP. All the fold change are iP vs. iNP fold change.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_017282.1NP_058978.1NC_005101.2 range: 203825059..203848377
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005634nucleusCellular ComponentIEA
GO:0005737cytoplasmCellular ComponentIEA
GO:0005829cytosolCellular ComponentIEA
GO:0005839proteasome core complexCellular ComponentIEA
GO:0004298threonine endopeptidase activityMolecular FunctionIEA
GO:0005515protein bindingMolecular FunctionISS
GO:0006511ubiquitin-dependent protein catabolic processBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:29672
RGD:61848
Ensembl:ENSRNOG00000019868
dbSNP:Psma5