| Gene Information |
| Gene ID: | | 3084 |
| Symbol: | | NRG1 |
| Full Name: | | neuregulin 1 |
| Alias: | | ARIA|GGF|GGF2|HGL|HRG|HRG1|HRGA|NDF|SMDF |
| Organism: | | Homo sapiens (Human) |
| Chromosome: | | 8 |
| Genetic Location: | | 8p12 |
| Physical Location: | | 31616809-32741614 on NC_000008.9 |
| Gene Type: | | protein-coding |
| Orthologs: | | This gene has no orthologs in other dataset(s). |
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| Gene in Ethanol Study Datasets |
| Gene Information | | | Dataset Information | | Name: | | Literature Search | | Method: | | Literature search | | Summary: | | We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive. |
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| Gene Refseq Sequence Annotation |
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| Gene Ontology (GO) Annotation |
| GO ID | GO Term | Category | Evidence (PubMed) | |
| GO:0016020 | membrane | Cellular Component | NAS (8096067) | |
| GO:0005576 | extracellular region | Cellular Component | NAS (1348215|1350381|8096067) | |
| GO:0005634 | nucleus | Cellular Component | IEA | |
| GO:0016021 | integral to membrane | Cellular Component | IEA | |
| GO:0030971 | receptor tyrosine kinase binding | Molecular Function | NAS (1348215|1350381) | |
| GO:0030297 | transmembrane receptor protein tyrosine kinase activator activity | Molecular Function | NAS (1348215|1350381) | |
| GO:0003674 | molecular_function | Molecular Function | ND | |
| GO:0008083 | growth factor activity | Molecular Function | NAS (8096067) | |
| GO:0008083 | growth factor activity | Molecular Function | IEA | |
| GO:0003712 | transcription cofactor activity | Molecular Function | IDA (15073182) | |
| GO:0009790 | embryonic development | Biological Process | IEA | |
| GO:0043624 | cellular protein complex disassembly | Biological Process | IGI (15155732) | |
| GO:0043497 | regulation of protein heterodimerization activity | Biological Process | IDA (10559227) | |
| GO:0007399 | nervous system development | Biological Process | NAS | |
| GO:0030154 | cell differentiation | Biological Process | NAS (7509448) | |
| GO:0016481 | negative regulation of transcription | Biological Process | IDA (15073182) | |
| GO:0051048 | negative regulation of secretion | Biological Process | IDA (10559227) | |
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| Other Database Cross Links |
| NCBI Entrez Gene: | | 3084 |
| HGNC: | | 7997 |
| Ensembl: | | ENSG00000157168 |
| MIM: | | 142445 |
| HPRD: | | 00802 |
| HuGE Navigator: | | 3084 |
| dbSNP: | | NRG1 |
| GeneCard: | | NRG1 |
| AceView: | | NRG1 |
