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Gene Information
Gene ID:3084
Symbol:NRG1
Full Name:neuregulin 1
Alias:ARIA|GGF|GGF2|HGL|HRG|HRG1|HRGA|NDF|SMDF
Organism:Homo sapiens (Human)
Chromosome:8
Genetic Location:8p12
Physical Location:31616809-32741614 on NC_000008.9
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:NRG1
Dataset Information
Name:Literature Search
Method:Literature search
Summary:We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_004495.2NP_004486.2NC_000008.9 range: 31616809..32741614
NM_013956.2NP_039250.2NC_000008.9 range: 31616809..32741614
NM_013957.2NP_039251.2NC_000008.9 range: 31616809..32741614
NM_013958.2NP_039252.2NC_000008.9 range: 31616809..32741614
NM_013959.2NP_039253.1NC_000008.9 range: 31616809..32741614
NM_013960.2NP_039254.1NC_000008.9 range: 31616809..32741614
NM_013962.2NP_039256.2NC_000008.9 range: 31616809..32741614
NM_013964.2NP_039258.1NC_000008.9 range: 31616809..32741614
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0016020membraneCellular ComponentNAS (8096067)
GO:0005576extracellular regionCellular ComponentNAS (1348215|1350381|8096067)
GO:0005634nucleusCellular ComponentIEA
GO:0016021integral to membraneCellular ComponentIEA
GO:0030971receptor tyrosine kinase bindingMolecular FunctionNAS (1348215|1350381)
GO:0030297transmembrane receptor protein tyrosine kinase activator activityMolecular FunctionNAS (1348215|1350381)
GO:0003674molecular_functionMolecular FunctionND
GO:0008083growth factor activityMolecular FunctionNAS (8096067)
GO:0008083growth factor activityMolecular FunctionIEA
GO:0003712transcription cofactor activityMolecular FunctionIDA (15073182)
GO:0009790embryonic developmentBiological ProcessIEA
GO:0043624cellular protein complex disassemblyBiological ProcessIGI (15155732)
GO:0043497regulation of protein heterodimerization activityBiological ProcessIDA (10559227)
GO:0007399nervous system developmentBiological ProcessNAS
GO:0030154cell differentiationBiological ProcessNAS (7509448)
GO:0016481negative regulation of transcriptionBiological ProcessIDA (15073182)
GO:0051048negative regulation of secretionBiological ProcessIDA (10559227)
Other Database Cross Links
NCBI Entrez Gene:3084
HGNC:7997
Ensembl:ENSG00000157168
MIM:142445
HPRD:00802
HuGE Navigator:3084
dbSNP:NRG1
GeneCard:NRG1
AceView:NRG1