ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Angptl3

Full Name:

angiopoietin-like 3

Alias:

hypl

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

4 C6|4 48.0 cM

Physical Location:

98697645-98704878 on NC_000070.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 27329 Symbol (Name): ANGPTL3 (angiopoietin-like 3)

Ortholog Status:

The human GeneID 27329 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Caws2	Chronic Alcohol Withdrawal	4		33-51 (cM)	2.3	0.005	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_013913.3	NP_038941.1	NC_000070.5 range: 98697645..98704878

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005576	extracellular region	Cellular Component	ISS (10644446)
GO:0004857	enzyme inhibitor activity	Molecular Function	IDA (12097324)
GO:0005102	receptor binding	Molecular Function	IEA
GO:0005178	integrin binding	Molecular Function	RCA (16141072)
GO:0045766	positive regulation of angiogenesis	Biological Process	RCA (16141072)
GO:0045834	positive regulation of lipid metabolic process	Biological Process	NAS (11788823)
GO:0048844	artery morphogenesis	Biological Process	IMP (12671033)
GO:0055090	acylglycerol homeostasis	Biological Process	IMP (17110602)
GO:0055091	phospholipid homeostasis	Biological Process	IMP (17110602)
GO:0042632	cholesterol homeostasis	Biological Process	IMP (17110602)
GO:0030335	positive regulation of cell migration	Biological Process	RCA (16141072)
GO:0016042	lipid catabolic process	Biological Process	RCA (16141072)
GO:0007229	integrin-mediated signaling pathway	Biological Process	RCA (16141072)
GO:0007165	signal transduction	Biological Process	IEA
GO:0007160	cell-matrix adhesion	Biological Process	RCA (16141072)
GO:0006641	triacylglycerol metabolic process	Biological Process	NAS (12097324)
GO:0060192	negative regulation of lipase activity	Biological Process	IMP (17110602)