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Gene Information
Gene ID:3105
Symbol:HLA-A
Full Name:major histocompatibility complex, class I, A
Organism:Homo sapiens (Human)
Chromosome:6
Genetic Location:6p21.3
Physical Location:30018309-30021632 on NC_000006.10
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:HLA-A
Dataset Information
Name:Literature Search
Method:Literature search
Summary:We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.
Gene Information
Original IDNo. of PublicationsPhenotype
HLA-A1Alcoholism
HLA-A1Alcohol-Related Disorders
HuGE Navigator Dataset
Name:HuGE Navigator
Method:Literature data mining
Publication:Wei Yu, Melinda Clyne, Anja Wulf, Ajay Yesupriya, Marta Gwinn and Muin J. Khoury. Phenopedia. HuGE Navigator. Available at: http://www.hugenavigator.net/HuGENavigator/startPagePhenoPedia.do. Accessed [Jun. 10, 2008].
Summary:HuGE Navigator Phenopedia provides a disease-centered view of genetic association studies summarized in the online Human Genome Epidemiology (HuGE) encyclopedia. We extracted genes associated to 9 Alcohol-related diseases (Alcohol Amnestic Disorder; Alcohol Withdrawal Delirium; Alcohol Withdrawal Seizures; Alcohol-Induced Disorders; Alcohol-Induced Disorders, Nervous System; Alcohol-Related Disorders; Alcoholic Intoxication; Alcoholic Neuropathy; Alcoholism) from HuGE Navigator Phenopedia.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_002116.5NP_002107.3NC_000006.10 range: 30018309..30021632
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0000139Golgi membraneCellular ComponentEXP (15569716)
GO:0031901early endosome membraneCellular ComponentEXP (15569716)
GO:0016021integral to membraneCellular ComponentIEA
GO:0016020membraneCellular ComponentIEA
GO:0005887integral to plasma membraneCellular ComponentNAS (1431115|2437024|2715640|6609814|8188325)
GO:0042612MHC class I protein complexCellular ComponentIEA
GO:0005515protein bindingMolecular FunctionIPI (12414957|17353931)
GO:0032393MHC class I receptor activityMolecular FunctionNAS (1431115|2437024|2715640|6609814|8188325)
GO:0006955immune responseBiological ProcessIEA
GO:0006955immune responseBiological ProcessNAS (1431115|2437024|2715640|6609814|8188325)
GO:0019882antigen processing and presentationBiological ProcessIEA
GO:0002474antigen processing and presentation of peptide antigen via MHC class IBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:3105
HGNC:4931
Ensembl:ENSG00000204632
MIM:142800
HPRD:00826
HuGE Navigator:3105
dbSNP:HLA-A
GeneCard:HLA-A
AceView:HLA-A