| Gene Information |
| Gene ID: | | 3106 |
| Symbol: | | HLA-B |
| Full Name: | | major histocompatibility complex, class I, B |
| Alias: | | AS|HLA B|HLAB|SPDA1 |
| Organism: | | Homo sapiens (Human) |
| Chromosome: | | 6 |
| Genetic Location: | | 6p21.3 |
| Physical Location: | | 31429627-31432913 on NC_000006.10, complement |
| Gene Type: | | protein-coding |
| Orthologs: | | This gene has no orthologs in other dataset(s). |
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| Gene in Ethanol Study Datasets |
| Gene Information | | | Dataset Information | | Name: | | Literature Search | | Method: | | Literature search | | Summary: | | We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive. |
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| Gene Information | | Original ID | No. of Publications | Phenotype | |
| HLA-B | 1 | Alcoholism | | HLA-B | 1 | Alcohol-Related Disorders |
| | HuGE Navigator Dataset | | Name: | | HuGE Navigator | | Method: | | Literature data mining | | Publication: | | Wei Yu, Melinda Clyne, Anja Wulf, Ajay Yesupriya, Marta Gwinn and Muin J. Khoury. Phenopedia. HuGE Navigator. Available at: http://www.hugenavigator.net/HuGENavigator/startPagePhenoPedia.do. Accessed [Jun. 10, 2008]. | | Summary: | | HuGE Navigator Phenopedia provides a disease-centered view of genetic association studies summarized in the online Human Genome Epidemiology (HuGE) encyclopedia. We extracted genes associated to 9 Alcohol-related diseases (Alcohol Amnestic Disorder; Alcohol Withdrawal Delirium; Alcohol Withdrawal Seizures; Alcohol-Induced Disorders; Alcohol-Induced Disorders, Nervous System; Alcohol-Related Disorders; Alcoholic Intoxication; Alcoholic Neuropathy; Alcoholism) from HuGE Navigator Phenopedia. |
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| Gene Refseq Sequence Annotation |
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| Gene Ontology (GO) Annotation |
| GO ID | GO Term | Category | Evidence (PubMed) | |
| GO:0005887 | integral to plasma membrane | Cellular Component | NAS (518865) | |
| GO:0016020 | membrane | Cellular Component | IEA | |
| GO:0016021 | integral to membrane | Cellular Component | IEA | |
| GO:0042612 | MHC class I protein complex | Cellular Component | IEA | |
| GO:0032393 | MHC class I receptor activity | Molecular Function | NAS (518865) | |
| GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I | Biological Process | IEA | |
| GO:0006955 | immune response | Biological Process | IEA | |
| GO:0006955 | immune response | Biological Process | NAS (518865) | |
| GO:0019882 | antigen processing and presentation | Biological Process | IEA | |
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| Other Database Cross Links |
| NCBI Entrez Gene: | | 3106 |
| HGNC: | | 4932 |
| Ensembl: | | ENSG00000204523 |
| MIM: | | 142830 |
| HPRD: | | 00828 |
| HuGE Navigator: | | 3106 |
| dbSNP: | | HLA-B |
| GeneCard: | | HLA-B |
| AceView: | | HLA-B |
