| Gene Information |
| Gene ID: | | 3146 |
| Symbol: | | HMGB1 |
| Full Name: | | high-mobility group box 1 |
| Alias: | | DKFZp686A04236|HMG1|HMG3|SBP-1 |
| Organism: | | Homo sapiens (Human) |
| Chromosome: | | 13 |
| Genetic Location: | | 13q12 |
| Physical Location: | | 29930876-29938080 on NC_000013.9, complement |
| Gene Type: | | protein-coding |
| Orthologs: | | This gene has no orthologs in other dataset(s). |
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| Gene in Ethanol Study Datasets |
| Gene Information | | | Dataset Information | | Name: | | Literature Search | | Method: | | Literature search | | Summary: | | We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive. |
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| Gene Refseq Sequence Annotation |
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| Gene Ontology (GO) Annotation |
| GO ID | GO Term | Category | Evidence (PubMed) | |
| GO:0000785 | chromatin | Cellular Component | IEA | |
| GO:0000793 | condensed chromosome | Cellular Component | IDA (12925773) | |
| GO:0005634 | nucleus | Cellular Component | IEA | |
| GO:0005634 | nucleus | Cellular Component | TAS (16130169) | |
| GO:0008134 | transcription factor binding | Molecular Function | TAS (11748232) | |
| GO:0008301 | DNA bending activity | Molecular Function | TAS (11246022) | |
| GO:0003677 | DNA binding | Molecular Function | IEA | |
| GO:0007165 | signal transduction | Biological Process | TAS (16130169) | |
| GO:0006916 | anti-apoptosis | Biological Process | TAS (16130169) | |
| GO:0006357 | regulation of transcription from RNA polymerase II promoter | Biological Process | IDA (11748232) | |
| GO:0006355 | regulation of transcription, DNA-dependent | Biological Process | IEA | |
| GO:0006325 | establishment and/or maintenance of chromatin architecture | Biological Process | TAS (11246022) | |
| GO:0006310 | DNA recombination | Biological Process | TAS (11748232) | |
| GO:0006288 | base-excision repair, DNA ligation | Biological Process | IDA (9600082) | |
| GO:0006281 | DNA repair | Biological Process | TAS (11748232) | |
| GO:0006268 | DNA unwinding during replication | Biological Process | NAS | |
| GO:0017055 | negative regulation of transcriptional preinitiation complex assembly | Biological Process | IDA (8006019) | |
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| Other Database Cross Links |
| NCBI Entrez Gene: | | 3146 |
| HGNC: | | 4983 |
| Ensembl: | | ENSG00000189403 |
| MIM: | | 163905 |
| HPRD: | | 01228 |
| HuGE Navigator: | | 3146 |
| dbSNP: | | HMGB1 |
| GeneCard: | | HMGB1 |
| AceView: | | HMGB1 |
