ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

HMGCS2

Full Name:

3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial)

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

1p13-p12

Physical Location:

120092524-120113040 on NC_000001.9, complement

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

HMGCS2

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_005518.2	NP_005509.1	NC_000001.9 range: 120092524..120113040, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005739	mitochondrion	Cellular Component	TAS (7851882)
GO:0005759	mitochondrial matrix	Cellular Component	EXP (11479731)
GO:0004421	hydroxymethylglutaryl-CoA synthase activity	Molecular Function	EXP (11479731)
GO:0004421	hydroxymethylglutaryl-CoA synthase activity	Molecular Function	IEA
GO:0016740	transferase activity	Molecular Function	IEA
GO:0006695	cholesterol biosynthetic process	Biological Process	IEA
GO:0008152	metabolic process	Biological Process	IEA
GO:0008299	isoprenoid biosynthetic process	Biological Process	IEA