ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Itpkb

Full Name:

inositol 1,4,5-trisphosphate 3-kinase B

Alias:

1110033J02Rik|E130307H12Rik

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

1 H5|1 100.0 cM

Physical Location:

182260606-182353789 on NC_000067.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 3707 Symbol (Name): ITPKB (inositol 1,4,5-trisphosphate 3-kinase B)

Ortholog Status:

The human GeneID 3707 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Calw1/Alcdp1	Chronic Alcohol Withdrawal	1	96	89-106.3 (cM)	7.6	2.00E-09	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_001081175.1	NP_001074644.1	NC_000067.5 range: 182260606..182353789

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0008440	inositol trisphosphate 3-kinase activity	Molecular Function	IDA (14517551)
GO:0008440	inositol trisphosphate 3-kinase activity	Molecular Function	IMP (15064401)
GO:0016301	kinase activity	Molecular Function	IEA
GO:0000165	MAPKKK cascade	Biological Process	IMP (15064401)
GO:0046579	positive regulation of Ras protein signal transduction	Biological Process	IMP (15064401)
GO:0045061	thymic T cell selection	Biological Process	IMP (14517551)
GO:0045059	positive thymic T cell selection	Biological Process	IMP (15064401)
GO:0030217	T cell differentiation	Biological Process	IMP (14517551)
GO:0007166	cell surface receptor linked signal transduction	Biological Process	IMP (15064401)
GO:0046638	positive regulation of alpha-beta T cell differentiation	Biological Process	IMP (15064401)