ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Pkn1

Full Name:

protein kinase N1

Alias:

DBK|F730027O18Rik|PAK1|PRK1|Pkn|Prkcl1|Stk3

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

8 C2

Physical Location:

86193994-86223024 on NC_000074.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 5585 Symbol (Name): PKN1 (protein kinase N1)

Ortholog Status:

The human GeneID 5585 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Caws3/Alcw6	Chronic Alcohol Withdrawal	8		16-43 (cM)	3.5	0.0003	Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_177262.3	NP_796236.2	NC_000074.5 range: 86193994..86223024, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0016023	cytoplasmic membrane-bounded vesicle	Cellular Component	IDA (12783890)
GO:0005622	intracellular	Cellular Component	RCA (16141072)
GO:0005737	cytoplasm	Cellular Component	IDA (12783890)
GO:0000166	nucleotide binding	Molecular Function	IEA
GO:0016301	kinase activity	Molecular Function	IEA
GO:0008233	peptidase activity	Molecular Function	IEA
GO:0016740	transferase activity	Molecular Function	IEA
GO:0005524	ATP binding	Molecular Function	IEA
GO:0004697	protein kinase C activity	Molecular Function	IEA
GO:0004674	protein serine/threonine kinase activity	Molecular Function	IEA
GO:0004672	protein kinase activity	Molecular Function	IMP (12783890)
GO:0006972	hyperosmotic response	Biological Process	IDA (12783890)
GO:0007165	signal transduction	Biological Process	RCA (16141072)
GO:0006468	protein amino acid phosphorylation	Biological Process	IEA