ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

HPRT1

Full Name:

hypoxanthine phosphoribosyltransferase 1 (Lesch-Nyhan syndrome)

Alias:

HGPRT|HPRT

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

Xq26.1

Physical Location:

133421922-133462361 on NC_000023.9

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

HPRT1

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_000194.2	NP_000185.1	NC_000023.9 range: 133421922..133462361

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005829	cytosol	Cellular Component	EXP (6300847)
GO:0005737	cytoplasm	Cellular Component	IDA (6300847)
GO:0042803	protein homodimerization activity	Molecular Function	IPI (8044844)
GO:0000287	magnesium ion binding	Molecular Function	IDA (10360366)
GO:0005515	protein binding	Molecular Function	IPI (17353931)
GO:0004422	hypoxanthine phosphoribosyltransferase activity	Molecular Function	IDA (6300847\|9521733)
GO:0004422	hypoxanthine phosphoribosyltransferase activity	Molecular Function	EXP (6300847)
GO:0016757	transferase activity, transferring glycosyl groups	Molecular Function	IEA
GO:0046100	hypoxanthine metabolic process	Biological Process	IMP (9824441)
GO:0045964	positive regulation of dopamine metabolic process	Biological Process	IMP (8643611)
GO:0009116	nucleoside metabolic process	Biological Process	IEA
GO:0007610	behavior	Biological Process	IMP (16138897)
GO:0006166	purine ribonucleoside salvage	Biological Process	IMP (9824441)
GO:0006164	purine nucleotide biosynthetic process	Biological Process	IMP (9824441)
GO:0051289	protein homotetramerization	Biological Process	IDA (9521733)