| Gene Information |
| Gene ID: | | 3362 |
| Symbol: | | HTR6 |
| Full Name: | | 5-hydroxytryptamine (serotonin) receptor 6 |
| Alias: | | 5-HT6|5-HT6R |
| Organism: | | Homo sapiens (Human) |
| Chromosome: | | 1 |
| Genetic Location: | | 1p36-p35 |
| Physical Location: | | 19864366-19878641 on NC_000001.9 |
| Gene Type: | | protein-coding |
| Orthologs: | | This gene has no orthologs in other dataset(s). |
|
| Gene in Ethanol Study Datasets |
| Gene Information | | Original ID | No. of Publications | Phenotype | |
| HTR6 | 2 | Alcoholism |
| | HuGE Navigator Dataset | | Name: | | HuGE Navigator | | Method: | | Literature data mining | | Publication: | | Wei Yu, Melinda Clyne, Anja Wulf, Ajay Yesupriya, Marta Gwinn and Muin J. Khoury. Phenopedia. HuGE Navigator. Available at: http://www.hugenavigator.net/HuGENavigator/startPagePhenoPedia.do. Accessed [Jun. 10, 2008]. | | Summary: | | HuGE Navigator Phenopedia provides a disease-centered view of genetic association studies summarized in the online Human Genome Epidemiology (HuGE) encyclopedia. We extracted genes associated to 9 Alcohol-related diseases (Alcohol Amnestic Disorder; Alcohol Withdrawal Delirium; Alcohol Withdrawal Seizures; Alcohol-Induced Disorders; Alcohol-Induced Disorders, Nervous System; Alcohol-Related Disorders; Alcoholic Intoxication; Alcoholic Neuropathy; Alcoholism) from HuGE Navigator Phenopedia. |
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|
| Gene Refseq Sequence Annotation |
|
| Gene Ontology (GO) Annotation |
| GO ID | GO Term | Category | Evidence (PubMed) | |
| GO:0005886 | plasma membrane | Cellular Component | IEA | |
| GO:0005887 | integral to plasma membrane | Cellular Component | TAS (8522988) | |
| GO:0001584 | rhodopsin-like receptor activity | Molecular Function | IEA | |
| GO:0004872 | receptor activity | Molecular Function | IEA | |
| GO:0004969 | histamine receptor activity | Molecular Function | TAS (8522988) | |
| GO:0005515 | protein binding | Molecular Function | IPI (17189269) | |
| GO:0007165 | signal transduction | Biological Process | IEA | |
| GO:0007187 | G-protein signaling, coupled to cyclic nucleotide second messenger | Biological Process | TAS (8522988) | |
| GO:0007268 | synaptic transmission | Biological Process | TAS (8522988) | |
|
| Other Database Cross Links |
| NCBI Entrez Gene: | | 3362 |
| HGNC: | | 5301 |
| Ensembl: | | ENSG00000158748 |
| MIM: | | 601109 |
| HPRD: | | 03066 |
| HuGE Navigator: | | 3362 |
| dbSNP: | | HTR6 |
| GeneCard: | | HTR6 |
| AceView: | | HTR6 |
