ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

HTR7

Full Name:

5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled)

Alias:

5-HT7

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

10q21-q24

Physical Location:

92490554-92607650 on NC_000010.9, complement

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

HTR7

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Information

HuGE Navigator Dataset

Name:		HuGE Navigator
Method:		Literature data mining
Publication:		Wei Yu, Melinda Clyne, Anja Wulf, Ajay Yesupriya, Marta Gwinn and Muin J. Khoury. Phenopedia. HuGE Navigator. Available at: http://www.hugenavigator.net/HuGENavigator/startPagePhenoPedia.do. Accessed [Jun. 10, 2008].
Summary:		HuGE Navigator Phenopedia provides a disease-centered view of genetic association studies summarized in the online Human Genome Epidemiology (HuGE) encyclopedia. We extracted genes associated to 9 Alcohol-related diseases (Alcohol Amnestic Disorder; Alcohol Withdrawal Delirium; Alcohol Withdrawal Seizures; Alcohol-Induced Disorders; Alcohol-Induced Disorders, Nervous System; Alcohol-Related Disorders; Alcoholic Intoxication; Alcoholic Neuropathy; Alcoholism) from HuGE Navigator Phenopedia.

Gene Refseq Sequence Annotation

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0016021	integral to membrane	Cellular Component	IEA
GO:0005887	integral to plasma membrane	Cellular Component	TAS (8226867)
GO:0005886	plasma membrane	Cellular Component	IEA
GO:0001584	rhodopsin-like receptor activity	Molecular Function	IEA
GO:0004993	serotonin receptor activity	Molecular Function	TAS (8226867)
GO:0004977	melanocortin receptor activity	Molecular Function	IEA
GO:0004872	receptor activity	Molecular Function	IEA
GO:0007186	G-protein coupled receptor protein signaling pathway	Biological Process	IEA
GO:0007187	G-protein signaling, coupled to cyclic nucleotide second messenger	Biological Process	TAS (8226867)
GO:0007268	synaptic transmission	Biological Process	TAS (8226867)
GO:0007623	circadian rhythm	Biological Process	TAS (8398139)
GO:0008015	blood circulation	Biological Process	TAS (8226867)
GO:0007165	signal transduction	Biological Process	IEA