ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

337

Symbol:

APOA4

Full Name:

apolipoprotein A-IV

Alias:

MGC142154|MGC142156

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

11q23

Physical Location:

116196627-116199220 on NC_000011.8, complement

Gene Type:

protein-coding

Orthologs:

This gene has Mouse: 11808 ortholog(s) in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

APOA4

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_000482.3	NP_000473.2	NC_000011.8 range: 116196627..116199220, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0042627	chylomicron	Cellular Component	IEA
GO:0005788	endoplasmic reticulum lumen	Cellular Component	EXP (12692552)
GO:0005615	extracellular space	Cellular Component	IDA (1935934)
GO:0005576	extracellular region	Cellular Component	NAS (14718574)
GO:0005576	extracellular region	Cellular Component	EXP (4345202\|12692552)
GO:0043499	eukaryotic cell surface binding	Molecular Function	IDA (1935934)
GO:0042803	protein homodimerization activity	Molecular Function	IDA (1935934)
GO:0030169	low-density lipoprotein binding	Molecular Function	IDA (16945374)
GO:0016209	antioxidant activity	Molecular Function	IDA (16945374)
GO:0008289	lipid binding	Molecular Function	IEA
GO:0031210	phosphatidylcholine binding	Molecular Function	IDA (1935934\|11940599)
GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity	Molecular Function	IDA (1935934)
GO:0005507	copper ion binding	Molecular Function	IDA (16945374)
GO:0005319	lipid transporter activity	Molecular Function	TAS (3080432)
GO:0046470	phosphatidylcholine metabolic process	Biological Process	IDA (1935934)
GO:0055088	lipid homeostasis	Biological Process	IDA (3095477)
GO:0043691	reverse cholesterol transport	Biological Process	IDA (3095477)
GO:0042744	hydrogen peroxide catabolic process	Biological Process	IDA (16945374)
GO:0042632	cholesterol homeostasis	Biological Process	IDA (1935934)
GO:0044240	multicellular organismal lipid catabolic process	Biological Process	IDA (3095477)
GO:0042160	lipoprotein modification	Biological Process	IDA (16945374)
GO:0006869	lipid transport	Biological Process	IEA
GO:0006982	response to lipid hydroperoxide	Biological Process	IDA (16945374)
GO:0007159	leukocyte adhesion	Biological Process	IDA (15254593)
GO:0008203	cholesterol metabolic process	Biological Process	IDA (1935934)
GO:0019430	removal of superoxide radicals	Biological Process	IDA (16945374)
GO:0002227	innate immune response in mucosa	Biological Process	IDA (15254593)
GO:0032374	regulation of cholesterol transport	Biological Process	IDA (11940599)
GO:0033344	cholesterol efflux	Biological Process	IDA (1935934\|11162594)
GO:0033700	phospholipid efflux	Biological Process	IDA (11162594)
GO:0065005	protein-lipid complex assembly	Biological Process	IMP (16159879)