ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

APOB

Full Name:

apolipoprotein B (including Ag(x) antigen)

Alias:

FLDB

Organism:

Homo sapiens (Human)

Chromosome:

2

Genetic Location:

2p24-p23

Physical Location:

21077805-21120449 on NC_000002.10, complement

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

APOB

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_000384.2	NP_000375.2	NC_000002.10 range: 21077805..21120449, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0010008	endosome membrane	Cellular Component	EXP (221835)
GO:0030669	clathrin-coated endocytic vesicle membrane	Cellular Component	EXP (221835)
GO:0031904	endosome lumen	Cellular Component	EXP (221835)
GO:0042627	chylomicron	Cellular Component	IEA
GO:0005886	plasma membrane	Cellular Component	EXP (221835\|8300609)
GO:0005792	microsome	Cellular Component	TAS (7853698)
GO:0005788	endoplasmic reticulum lumen	Cellular Component	EXP (12692552)
GO:0005576	extracellular region	Cellular Component	IEA
GO:0005576	extracellular region	Cellular Component	EXP (4345202\|8300609\|9548923\|12692552)
GO:0046982	protein heterodimerization activity	Molecular Function	IPI (8245722)
GO:0017127	cholesterol transporter activity	Molecular Function	IMP (15797858)
GO:0005319	lipid transporter activity	Molecular Function	IEA
GO:0050750	low-density lipoprotein receptor binding	Molecular Function	IMP (2563166\|15797858)
GO:0008201	heparin binding	Molecular Function	IEA
GO:0005543	phospholipid binding	Molecular Function	IDA (7126555)
GO:0008203	cholesterol metabolic process	Biological Process	IEA
GO:0030301	cholesterol transport	Biological Process	IMP (2563166)
GO:0006869	lipid transport	Biological Process	IEA
GO:0006629	lipid metabolic process	Biological Process	IEA
GO:0042632	cholesterol homeostasis	Biological Process	IMP (2563166)
GO:0008202	steroid metabolic process	Biological Process	IEA

Other Database Cross Links

NCBI Entrez Gene:

HGNC:

Ensembl:

ENSG00000084674

MIM:

HPRD:

HuGE Navigator:

dbSNP:

GeneCard:

AceView: