ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

IDE

Full Name:

insulin-degrading enzyme

Alias:

FLJ35968|INSULYSIN

Organism:

Homo sapiens (Human)

Chromosome:

10

Genetic Location:

10q23-q25

Physical Location:

94203579-94323831 on NC_000010.9, complement

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

IDE

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_004969.2	NP_004960.2	NC_000010.9 range: 94203579..94323831, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005615	extracellular space	Cellular Component	TAS (9830016)
GO:0005625	soluble fraction	Cellular Component	TAS (9830016)
GO:0005737	cytoplasm	Cellular Component	IEA
GO:0005777	peroxisome	Cellular Component	TAS (8425612)
GO:0004231	insulysin activity	Molecular Function	TAS (2293021)
GO:0008270	zinc ion binding	Molecular Function	IEA
GO:0046872	metal ion binding	Molecular Function	IEA
GO:0004871	signal transducer activity	Molecular Function	TAS (2293021\|3059494)
GO:0007165	signal transduction	Biological Process	NAS (2293021)
GO:0007267	cell-cell signaling	Biological Process	NR
GO:0007548	sex differentiation	Biological Process	TAS (8425612)
GO:0006508	proteolysis	Biological Process	TAS (9830016)

Other Database Cross Links

NCBI Entrez Gene:

HGNC:

Ensembl:

ENSG00000119912

MIM:

HPRD:

HuGE Navigator:

dbSNP:

GeneCard:

AceView: