ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

IDH2

Full Name:

isocitrate dehydrogenase 2 (NADP+), mitochondrial

Alias:

ICD-M|IDH|IDHM|IDP|mNADP-IDH

Organism:

Homo sapiens (Human)

Chromosome:

15

Genetic Location:

15q26.1

Physical Location:

88428213-88446711 on NC_000015.8, complement

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

IDH2

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_002168.2	NP_002159.2	NC_000015.8 range: 88428213..88446711, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005739	mitochondrion	Cellular Component	IDA (8707889)
GO:0005739	mitochondrion	Cellular Component	IEA
GO:0000287	magnesium ion binding	Molecular Function	IEA
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	Molecular Function	IEA
GO:0016491	oxidoreductase activity	Molecular Function	IEA
GO:0030145	manganese ion binding	Molecular Function	IEA
GO:0004450	isocitrate dehydrogenase (NADP+) activity	Molecular Function	NAS (8707889)
GO:0004450	isocitrate dehydrogenase (NADP+) activity	Molecular Function	IEA
GO:0005975	carbohydrate metabolic process	Biological Process	NAS (8954790)
GO:0006099	tricarboxylic acid cycle	Biological Process	IEA
GO:0008152	metabolic process	Biological Process	IEA
GO:0008152	metabolic process	Biological Process	NAS (8707889)
GO:0006097	glyoxylate cycle	Biological Process	IEA

Other Database Cross Links

NCBI Entrez Gene:

HGNC:

Ensembl:

ENSG00000182054

MIM:

HPRD:

HuGE Navigator:

dbSNP:

GeneCard:

AceView: