ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

APOC3

Full Name:

apolipoprotein C-III

Alias:

APOCIII|MGC150353

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

11q23.1-q23.2

Physical Location:

116205833-116208996 on NC_000011.8

Gene Type:

protein-coding

Orthologs:

This gene has Mouse: 11814 ortholog(s) in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

APOC3

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_000040.1	NP_000031.1	NC_000011.8 range: 116205833..116208996

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0042627	chylomicron	Cellular Component	IEA
GO:0005576	extracellular region	Cellular Component	EXP (4345202)
GO:0005576	extracellular region	Cellular Component	IEA
GO:0005615	extracellular space	Cellular Component	IDA (11060345)
GO:0005615	extracellular space	Cellular Component	IMP (17438339)
GO:0030234	enzyme regulator activity	Molecular Function	IDA (11060345)
GO:0015485	cholesterol binding	Molecular Function	TAS (16973241)
GO:0015485	cholesterol binding	Molecular Function	IC (11162594)
GO:0005319	lipid transporter activity	Molecular Function	IEA
GO:0005543	phospholipid binding	Molecular Function	IDA (4066713\|11060345)
GO:0045717	negative regulation of fatty acid biosynthetic process	Biological Process	IDA (11060345)
GO:0042157	lipoprotein metabolic process	Biological Process	IEA
GO:0033700	phospholipid efflux	Biological Process	IDA (11162594)
GO:0033344	cholesterol efflux	Biological Process	IDA (11162594\|16443932)
GO:0032488	Cdc42 protein signal transduction	Biological Process	IDA (16443932)
GO:0019433	triacylglycerol catabolic process	Biological Process	IDA (11060345)
GO:0016042	lipid catabolic process	Biological Process	IEA
GO:0007186	G-protein coupled receptor protein signaling pathway	Biological Process	IDA (16443932)
GO:0006869	lipid transport	Biological Process	IEA
GO:0051005	negative regulation of lipoprotein lipase activity	Biological Process	IDA (11060345)