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Gene Information
Gene ID:347688
Symbol:RP11-631M21.2
Alias:FLJ40100|TUBB8
Organism:Homo sapiens (Human)
Chromosome:10
Genetic Location:10p15.3
Physical Location:82996-85177 on NC_000010.9, complement
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Linkage Dataset
MarkerLODP valueLocation (bp)
D10S249  270791
Region:1-2270791
Phenotype:Alcoholism phenotype along with age, gender, and P300 or constraint
Name:15211641
Method:Linkage
Publication:Hill et al. Am J Med Genet B Neuropsychiatr Genet. (2004) A genome wide search for alcoholism susceptibility genes. PubMed
Summary:A total of 360 markers for 22 autosomes were spaced at an average distance of 9.4cMand genotyping performed for 330 members of these multiplex families. Extensive clinical data, personality variation, and event-related potential characteristics were available for reducing heterogeneity and detecting robust linkage signals. Multipoint linkage analysis using different analytic strategies give strong support for loci on chromosomes 1, 2, 6, 7, 10, 12, 14, 16, and 17. Thirty five markers with LOD score >2.0 at baseline using the binary alcoholism phenotype along with age, gender, and P300 or constraint (Table III). Here we listed the genes between two near markers or genes near a separate marker (within 2Mb).
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_177987.1NP_817124.1NC_000010.9 range: 82996..85177, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005737cytoplasmCellular ComponentIEA
GO:0005874microtubuleCellular ComponentIEA
GO:0043234protein complexCellular ComponentIEA
GO:0000166nucleotide bindingMolecular FunctionIEA
GO:0003924GTPase activityMolecular FunctionIEA
GO:0005198structural molecule activityMolecular FunctionIEA
GO:0005525GTP bindingMolecular FunctionIEA
GO:0007018microtubule-based movementBiological ProcessIEA
GO:0051258protein polymerizationBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:347688
HGNC:
Ensembl:ENSG00000173876
MIM:
HPRD:18244
HuGE Navigator:347688
dbSNP:RP11-631M21.2
GeneCard:RP11-631M21.2
AceView:RP11-631M21.2