| Gene Information |
| Gene ID: | | 3486 |
| Symbol: | | IGFBP3 |
| Full Name: | | insulin-like growth factor binding protein 3 |
| Alias: | | BP-53|IBP3 |
| Organism: | | Homo sapiens (Human) |
| Chromosome: | | 7 |
| Genetic Location: | | 7p13-p12 |
| Physical Location: | | 45918368-45927395 on NC_000007.12, complement |
| Gene Type: | | protein-coding |
| Orthologs: | | This gene has no orthologs in other dataset(s). |
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| Gene in Ethanol Study Datasets |
| Gene Information | | | Dataset Information | | Name: | | Literature Search | | Method: | | Literature search | | Summary: | | We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive. |
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| Gene Refseq Sequence Annotation |
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| Gene Ontology (GO) Annotation |
| GO ID | GO Term | Category | Evidence (PubMed) | |
| GO:0005634 | nucleus | Cellular Component | IDA (17434920) | |
| GO:0005576 | extracellular region | Cellular Component | NAS (14718574) | |
| GO:0005576 | extracellular region | Cellular Component | IEA | |
| GO:0008160 | protein tyrosine phosphatase activator activity | Molecular Function | IDA (11940579) | |
| GO:0046872 | metal ion binding | Molecular Function | NAS (14576163) | |
| GO:0005520 | insulin-like growth factor binding | Molecular Function | NAS (12599210) | |
| GO:0005520 | insulin-like growth factor binding | Molecular Function | IEA | |
| GO:0001933 | negative regulation of protein amino acid phosphorylation | Biological Process | IDA (17591901) | |
| GO:0009968 | negative regulation of signal transduction | Biological Process | NAS (11940579) | |
| GO:0043065 | positive regulation of apoptosis | Biological Process | IMP (11971816) | |
| GO:0045663 | positive regulation of myoblast differentiation | Biological Process | IDA (12599210) | |
| GO:0001558 | regulation of cell growth | Biological Process | IEA | |
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| Other Database Cross Links |
| NCBI Entrez Gene: | | 3486 |
| HGNC: | | 5472 |
| Ensembl: | | ENSG00000146674 |
| MIM: | | 146732 |
| HPRD: | | 00899 |
| HuGE Navigator: | | 3486 |
| dbSNP: | | IGFBP3 |
| GeneCard: | | IGFBP3 |
| AceView: | | IGFBP3 |
