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Gene Information
Gene ID:3552
Symbol:IL1A
Full Name:interleukin 1, alpha
Alias:IL-1A|IL1|IL1-ALPHA|IL1F1
Organism:Homo sapiens (Human)
Chromosome:2
Genetic Location:2q14
Physical Location:113247962-113259441 on NC_000002.10, complement
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:IL1A
Dataset Information
Name:Literature Search
Method:Literature search
Summary:We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.
Gene Information
Original IDNo. of PublicationsPhenotype
IL1A1Alcohol-Induced Disorders
IL1A1Alcoholism
IL1A2Alcohol-Related Disorders
HuGE Navigator Dataset
Name:HuGE Navigator
Method:Literature data mining
Publication:Wei Yu, Melinda Clyne, Anja Wulf, Ajay Yesupriya, Marta Gwinn and Muin J. Khoury. Phenopedia. HuGE Navigator. Available at: http://www.hugenavigator.net/HuGENavigator/startPagePhenoPedia.do. Accessed [Jun. 10, 2008].
Summary:HuGE Navigator Phenopedia provides a disease-centered view of genetic association studies summarized in the online Human Genome Epidemiology (HuGE) encyclopedia. We extracted genes associated to 9 Alcohol-related diseases (Alcohol Amnestic Disorder; Alcohol Withdrawal Delirium; Alcohol Withdrawal Seizures; Alcohol-Induced Disorders; Alcohol-Induced Disorders, Nervous System; Alcohol-Related Disorders; Alcoholic Intoxication; Alcoholic Neuropathy; Alcoholism) from HuGE Navigator Phenopedia.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_000575.3NP_000566.3NC_000002.10 range: 113247962..113259441, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005576extracellular regionCellular ComponentIEA
GO:0005615extracellular spaceCellular ComponentTAS (1924307)
GO:0005737cytoplasmCellular ComponentNR
GO:0004871signal transducer activityMolecular FunctionTAS (10748004|10861041)
GO:0005149interleukin-1 receptor bindingMolecular FunctionIEA
GO:0001660feverBiological ProcessIEA
GO:0007267cell-cell signalingBiological ProcessNR
GO:0006955immune responseBiological ProcessIEA
GO:0006954inflammatory responseBiological ProcessTAS (6209582)
GO:0006935chemotaxisBiological ProcessNR
GO:0006916anti-apoptosisBiological ProcessTAS (10748004)
GO:0006915apoptosisBiological ProcessTAS (1924307)
GO:0008285negative regulation of cell proliferationBiological ProcessTAS (3493774)
Other Database Cross Links
NCBI Entrez Gene:3552
HGNC:5991
Ensembl:ENSG00000115008
MIM:147760
HPRD:00988
HuGE Navigator:3552
dbSNP:IL1A
GeneCard:IL1A
AceView:IL1A