Logo
Home Search BLAST Integration Document Link Support Citation

Gene Information
Gene ID:3607
Symbol:FOXK2
Full Name:forkhead box K2
Alias:ILF|ILF-1|ILF1
Organism:Homo sapiens (Human)
Chromosome:17
Genetic Location:17q25
Physical Location:78070882-78155771 on NC_000017.9
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Linkage Dataset
MarkerLODP valueLocation (bp)
D17S928  77846128
Region:75846128-78774742
Phenotype:Alcoholism phenotype along with age, gender, and P300 or constraint
Name:15211641
Method:Linkage
Publication:Hill et al. Am J Med Genet B Neuropsychiatr Genet. (2004) A genome wide search for alcoholism susceptibility genes. PubMed
Summary:A total of 360 markers for 22 autosomes were spaced at an average distance of 9.4cMand genotyping performed for 330 members of these multiplex families. Extensive clinical data, personality variation, and event-related potential characteristics were available for reducing heterogeneity and detecting robust linkage signals. Multipoint linkage analysis using different analytic strategies give strong support for loci on chromosomes 1, 2, 6, 7, 10, 12, 14, 16, and 17. Thirty five markers with LOD score >2.0 at baseline using the binary alcoholism phenotype along with age, gender, and P300 or constraint (Table III). Here we listed the genes between two near markers or genes near a separate marker (within 2Mb).
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_004514.3NP_004505.2NC_000017.9 range: 78070882..78155771
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005634nucleusCellular ComponentIC (1909027)
GO:0000287magnesium ion bindingMolecular FunctionIDA (16624804)
GO:0003700transcription factor activityMolecular FunctionNAS (12402362)
GO:0003702RNA polymerase II transcription factor activityMolecular FunctionTAS (1909027)
GO:0043565sequence-specific DNA bindingMolecular FunctionIDA (1339390|1909027|12402362|16624804)
GO:0006350transcriptionBiological ProcessIEA
GO:0006357regulation of transcription from RNA polymerase II promoterBiological ProcessTAS (1909027)
Other Database Cross Links
NCBI Entrez Gene:3607
HGNC:6036
Ensembl:ENSG00000141568
MIM:147685
HPRD:00982
HuGE Navigator:3607
dbSNP:FOXK2
GeneCard:FOXK2
AceView:FOXK2