| Gene Information |
| Gene ID: | | 3655 |
| Symbol: | | ITGA6 |
| Full Name: | | integrin, alpha 6 |
| Alias: | | CD49f|ITGA6B|VLA-6 |
| Organism: | | Homo sapiens (Human) |
| Chromosome: | | 2 |
| Genetic Location: | | 2q31.1 |
| Physical Location: | | 173000559-173079426 on NC_000002.10 |
| Gene Type: | | protein-coding |
| Orthologs: | | This gene has no orthologs in other dataset(s). |
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| Gene in Ethanol Study Datasets |
| Gene Information | | | Dataset Information | | Name: | | Literature Search | | Method: | | Literature search | | Summary: | | We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive. |
| | Gene Information | | Original ID1: | | H16046 | | Fold Change: | | 0.7 | | P Value: | | 0.03 | | Tissue: | | Nucleus accumbens |
| | Dataset Information | | Name: | | 15816859 | | Method: | | Microarray | | Tissue: | | Prefrontal cortex and nucleus accumbens | | Phenotype: | | Alcohol dependence (AD)/Alcohol abuse/Alcoholism | | Publication: | | Flatscher-Bader et al. J Neurochem.(2005) Alcohol-responsive genes in the frontal cortex and nucleus accumbens of human alcoholics. PubMed | | Summary: | | Genes with a mean fold change > 1.5 or < 0.7 were selected and annotated. Values are taken from microarray analysis and represent mean ratios of alcoholic cases compared with matched control cases(n = 6). P values were from t-test. |
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| Gene Refseq Sequence Annotation |
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| Gene Ontology (GO) Annotation |
| GO ID | GO Term | Category | Evidence (PubMed) | |
| GO:0016021 | integral to membrane | Cellular Component | IEA | |
| GO:0016020 | membrane | Cellular Component | IEA | |
| GO:0008305 | integrin complex | Cellular Component | IEA | |
| GO:0004872 | receptor activity | Molecular Function | IEA | |
| GO:0005515 | protein binding | Molecular Function | IEA | |
| GO:0005509 | calcium ion binding | Molecular Function | IEA | |
| GO:0007155 | cell adhesion | Biological Process | IEA | |
| GO:0007044 | cell-substrate junction assembly | Biological Process | TAS (9185503) | |
| GO:0007229 | integrin-mediated signaling pathway | Biological Process | IEA | |
| GO:0007160 | cell-matrix adhesion | Biological Process | NR | |
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| Other Database Cross Links |
| NCBI Entrez Gene: | | 3655 |
| HGNC: | | 6142 |
| Ensembl: | | ENSG00000091409 |
| MIM: | | 147556 |
| HPRD: | | 00945 |
| HuGE Navigator: | | 3655 |
| dbSNP: | | ITGA6 |
| GeneCard: | | ITGA6 |
| AceView: | | ITGA6 |
