ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Full Name:

androgen receptor (dihydrotestosterone receptor; testicular feminization; spinal and bulbar muscular atrophy; Kennedy disease)

Alias:

AIS|DHTR|HUMARA|KD|NR3C4|SBMA|SMAX1|TFM

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

Xq11.2-q12

Physical Location:

66680598-66860843 on NC_000023.9

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Information

HuGE Navigator Dataset

Name:		HuGE Navigator
Method:		Literature data mining
Publication:		Wei Yu, Melinda Clyne, Anja Wulf, Ajay Yesupriya, Marta Gwinn and Muin J. Khoury. Phenopedia. HuGE Navigator. Available at: http://www.hugenavigator.net/HuGENavigator/startPagePhenoPedia.do. Accessed [Jun. 10, 2008].
Summary:		HuGE Navigator Phenopedia provides a disease-centered view of genetic association studies summarized in the online Human Genome Epidemiology (HuGE) encyclopedia. We extracted genes associated to 9 Alcohol-related diseases (Alcohol Amnestic Disorder; Alcohol Withdrawal Delirium; Alcohol Withdrawal Seizures; Alcohol-Induced Disorders; Alcohol-Induced Disorders, Nervous System; Alcohol-Related Disorders; Alcoholic Intoxication; Alcoholic Neuropathy; Alcoholism) from HuGE Navigator Phenopedia.

Gene Refseq Sequence Annotation

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005737	cytoplasm	Cellular Component	IDA (15572661)
GO:0005634	nucleus	Cellular Component	IDA (15572661)
GO:0003700	transcription factor activity	Molecular Function	IDA (15572661)
GO:0046872	metal ion binding	Molecular Function	IEA
GO:0043565	sequence-specific DNA binding	Molecular Function	IEA
GO:0008270	zinc ion binding	Molecular Function	IEA
GO:0046983	protein dimerization activity	Molecular Function	NAS (10075738)
GO:0005497	androgen binding	Molecular Function	NAS (10075738)
GO:0004872	receptor activity	Molecular Function	IEA
GO:0004882	androgen receptor activity	Molecular Function	NAS (10075738)
GO:0004882	androgen receptor activity	Molecular Function	TAS (15572661)
GO:0005102	receptor binding	Molecular Function	IPI (11875111)
GO:0007267	cell-cell signaling	Biological Process	TAS (10835690)
GO:0007548	sex differentiation	Biological Process	NAS (10075738)
GO:0008283	cell proliferation	Biological Process	NAS (10075738)
GO:0016049	cell growth	Biological Process	NAS (15572661)
GO:0030850	prostate gland development	Biological Process	NAS (10075738)
GO:0006810	transport	Biological Process	TAS (10835690)
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	IEA
GO:0007165	signal transduction	Biological Process	TAS (10835690)