ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

JAK2

Full Name:

Janus kinase 2 (a protein tyrosine kinase)

Alias:

JTK10

Organism:

Homo sapiens (Human)

Chromosome:

9

Genetic Location:

9p24

Physical Location:

4975244-5117994 on NC_000009.10

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

JAK2

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_004972.2	NP_004963.1	NC_000009.10 range: 4975244..5117994

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0012505	endomembrane system	Cellular Component	IEA
GO:0005856	cytoskeleton	Cellular Component	IEA
GO:0000166	nucleotide binding	Molecular Function	IEA
GO:0016740	transferase activity	Molecular Function	IEA
GO:0042169	SH2 domain binding	Molecular Function	IPI (9727029)
GO:0005524	ATP binding	Molecular Function	IEA
GO:0005102	receptor binding	Molecular Function	IPI (11201744)
GO:0004713	protein-tyrosine kinase activity	Molecular Function	IEA
GO:0004718	Janus kinase activity	Molecular Function	IEA
GO:0004715	non-membrane spanning protein tyrosine kinase activity	Molecular Function	IEA
GO:0007498	mesoderm development	Biological Process	TAS (9590174)
GO:0007259	JAK-STAT cascade	Biological Process	TAS (9670957)
GO:0007242	intracellular signaling cascade	Biological Process	TAS (9590174)
GO:0006928	cell motility	Biological Process	TAS (9670957)
GO:0006468	protein amino acid phosphorylation	Biological Process	IEA
GO:0006468	protein amino acid phosphorylation	Biological Process	TAS (9670957)

Other Database Cross Links

NCBI Entrez Gene:

HGNC:

Ensembl:

ENSG00000096968

MIM:

HPRD:

HuGE Navigator:

dbSNP:

GeneCard:

AceView: