ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

ARF3

Full Name:

ADP-ribosylation factor 3

Organism:

Homo sapiens (Human)

Chromosome:

12

Genetic Location:

12q13

Physical Location:

47616258-47637576 on NC_000012.10, complement

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		M74491
Fold Change:		-1.5, -1.4
Note:		Differential expression on the oligonucleotide array (two fold changes are from two case groups)

Dataset Information

Name:		11141048
Method:		Microarray
Tissue:		Frontal cortex
Phenotype:		Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:		Lewohl et al. Alcohol Clin Exp Res. (2000) Gene expression in human alcoholism: microarray analysis of frontal cortex. PubMed
Summary:		RNA was extracted from postmortem samples of superior frontal cortex of alcoholics and nonalcoholics. Relative levels of RNA were determined by array techniques. This study used both cDNA and oligonucleotide microarrays to provide coverage of a large number of genes and to allow cross-validation for those genes represented on both types of arrays. Expression levels were determined for over 4000 genes and 163 of these were found to differ by 40% or more between alcoholics and nonalcoholics.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_001659.2	NP_001650.1	NC_000012.10 range: 47616258..47637576, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005622	intracellular	Cellular Component	IEA
GO:0005794	Golgi apparatus	Cellular Component	IEA
GO:0000166	nucleotide binding	Molecular Function	IEA
GO:0003924	GTPase activity	Molecular Function	TAS (1744102)
GO:0005525	GTP binding	Molecular Function	TAS (8947846)
GO:0007264	small GTPase mediated signal transduction	Biological Process	IEA
GO:0015031	protein transport	Biological Process	IEA
GO:0016192	vesicle-mediated transport	Biological Process	IEA

Other Database Cross Links

NCBI Entrez Gene:

HGNC:

Ensembl:

ENSG00000134287

MIM:

HPRD:

HuGE Navigator:

dbSNP:

GeneCard:

AceView: