ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Zhx2

Full Name:

zinc fingers and homeoboxes 2

Alias:

Afr-1|Afr1|Raf|mKIAA0854

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

15 D1|15 28.4 cM

Physical Location:

57526221-57671386 on NC_000081.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 22882 Symbol (Name): ZHX2 (zinc fingers and homeoboxes 2)

Ortholog Status:

The human GeneID 22882 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Lore5	Alcohol-induced Loss of Righting Reflex	15		18.8-61.7 (cM)	4		Significant	PARC
Aaq1/Etacc	Alcohol Acceptance	15	30	15-48 (cM)	3.8		Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_199449.2	NP_955520.1	NC_000081.5 range: 57526221..57671386

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005622	intracellular	Cellular Component	IEA
GO:0005634	nucleus	Cellular Component	IEA
GO:0005575	cellular_component	Cellular Component	ND
GO:0043565	sequence-specific DNA binding	Molecular Function	IEA
GO:0046872	metal ion binding	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	IPI (14659886)
GO:0003700	transcription factor activity	Molecular Function	IEA
GO:0003677	DNA binding	Molecular Function	IEA
GO:0008270	zinc ion binding	Molecular Function	IEA
GO:0045449	regulation of transcription	Biological Process	IEA
GO:0006402	mRNA catabolic process	Biological Process	IDA (1370712)
GO:0006357	regulation of transcription from RNA polymerase II promoter	Biological Process	IMP (7523852)
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	IEA
GO:0006350	transcription	Biological Process	IEA
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	Biological Process	IMP (10673330)