ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

LMO2

Full Name:

LIM domain only 2 (rhombotin-like 1)

Alias:

RBTN2|RBTNL1|RHOM2|TTG2

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

11p13

Physical Location:

33836697-33870411 on NC_000011.8, complement

Gene Type:

protein-coding

Orthologs:

This gene has Mouse: 16909 ortholog(s) in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		X61118
Fold Change:		-2.3, -1.8
Note:		Differential Expression on the cDNA array (two fold changes are from two case groups)

Dataset Information

Name:		11141048
Method:		Microarray
Tissue:		Frontal cortex
Phenotype:		Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:		Lewohl et al. Alcohol Clin Exp Res. (2000) Gene expression in human alcoholism: microarray analysis of frontal cortex. PubMed
Summary:		RNA was extracted from postmortem samples of superior frontal cortex of alcoholics and nonalcoholics. Relative levels of RNA were determined by array techniques. This study used both cDNA and oligonucleotide microarrays to provide coverage of a large number of genes and to allow cross-validation for those genes represented on both types of arrays. Expression levels were determined for over 4000 genes and 163 of these were found to differ by 40% or more between alcoholics and nonalcoholics.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_005574.2	NP_005565.1	NC_000011.8 range: 33836697..33870411, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	IEA
GO:0005515	protein binding	Molecular Function	ISS
GO:0008270	zinc ion binding	Molecular Function	IEA
GO:0046872	metal ion binding	Molecular Function	IEA
GO:0007275	multicellular organismal development	Biological Process	TAS (1923511)