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Gene Information
Gene ID:400745
Symbol:SH2D5
Full Name:SH2 domain containing 5
Alias:FLJ41242|FLJ41847|FLJ42879
Organism:Homo sapiens (Human)
Chromosome:1
Genetic Location:1p36.12
Physical Location:20918811-20931719 on NC_000001.9, complement
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:AI937119
Fold Change:1.5, 1.6
Note:Differential Expression on the cDNA array (two fold changes are from two case groups)
Dataset Information
Name:11141048
Method:Microarray
Tissue:Frontal cortex
Phenotype:Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:Lewohl et al. Alcohol Clin Exp Res. (2000) Gene expression in human alcoholism: microarray analysis of frontal cortex. PubMed
Summary:RNA was extracted from postmortem samples of superior frontal cortex of alcoholics and nonalcoholics. Relative levels of RNA were determined by array techniques. This study used both cDNA and oligonucleotide microarrays to provide coverage of a large number of genes and to allow cross-validation for those genes represented on both types of arrays. Expression levels were determined for over 4000 genes and 163 of these were found to differ by 40% or more between alcoholics and nonalcoholics.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_001103160.1NP_001096630.1NC_000001.9 range: 20918811..20931719, complement
NM_001103161.1NP_001096631.1NC_000001.9 range: 20918811..20931719, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005515protein bindingMolecular FunctionIEA
Other Database Cross Links
NCBI Entrez Gene:400745
HGNC:28819
Ensembl:ENSG00000189410
MIM:
HPRD:
HuGE Navigator:400745
dbSNP:SH2D5
GeneCard:SH2D5
AceView:SH2D5