ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

LPL

Full Name:

lipoprotein lipase

Alias:

HDLCQ11|LIPD

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

8p22

Physical Location:

19840861-19869049 on NC_000008.9

Gene Type:

protein-coding

Orthologs:

This gene has Mouse: 16956 ortholog(s) in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

LPL

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Information

Original ID	No. of Publications	Phenotype
LPL	1	Alcoholism

HuGE Navigator Dataset

Name:		HuGE Navigator
Method:		Literature data mining
Publication:		Wei Yu, Melinda Clyne, Anja Wulf, Ajay Yesupriya, Marta Gwinn and Muin J. Khoury. Phenopedia. HuGE Navigator. Available at: http://www.hugenavigator.net/HuGENavigator/startPagePhenoPedia.do. Accessed [Jun. 10, 2008].
Summary:		HuGE Navigator Phenopedia provides a disease-centered view of genetic association studies summarized in the online Human Genome Epidemiology (HuGE) encyclopedia. We extracted genes associated to 9 Alcohol-related diseases (Alcohol Amnestic Disorder; Alcohol Withdrawal Delirium; Alcohol Withdrawal Seizures; Alcohol-Induced Disorders; Alcohol-Induced Disorders, Nervous System; Alcohol-Related Disorders; Alcoholic Intoxication; Alcoholic Neuropathy; Alcoholism) from HuGE Navigator Phenopedia.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_000237.2	NP_000228.1	NC_000008.9 range: 19840861..19869049

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0042627	chylomicron	Cellular Component	IEA
GO:0031225	anchored to membrane	Cellular Component	IEA
GO:0005576	extracellular region	Cellular Component	TAS (1969408)
GO:0005886	plasma membrane	Cellular Component	IEA
GO:0016787	hydrolase activity	Molecular Function	IEA
GO:0008201	heparin binding	Molecular Function	TAS (1969408)
GO:0004465	lipoprotein lipase activity	Molecular Function	IEA
GO:0005319	lipid transporter activity	Molecular Function	IEA
GO:0005102	receptor binding	Molecular Function	IPI (10085125)
GO:0004806	triacylglycerol lipase activity	Molecular Function	ISS (10727238)
GO:0004620	phospholipase activity	Molecular Function	ISS (10727238)
GO:0006631	fatty acid metabolic process	Biological Process	NR
GO:0006644	phospholipid metabolic process	Biological Process	ISS (10727238)
GO:0008015	blood circulation	Biological Process	TAS (1969408)
GO:0016042	lipid catabolic process	Biological Process	IEA
GO:0006641	triacylglycerol metabolic process	Biological Process	ISS (10727238)