ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

LTK

Full Name:

leukocyte receptor tyrosine kinase

Alias:

TYK1

Organism:

Homo sapiens (Human)

Chromosome:

15

Genetic Location:

15q15.1-q21.1

Physical Location:

39583131-39593368 on NC_000015.8, complement

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

LTK

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_002344.4	NP_002335.2	NC_000015.8 range: 39583131..39593368, complement
NM_206961.2	NP_996844.1	NC_000015.8 range: 39583131..39593368, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005886	plasma membrane	Cellular Component	TAS (7685902)
GO:0005887	integral to plasma membrane	Cellular Component	TAS (7685902)
GO:0005625	soluble fraction	Cellular Component	TAS (7685902)
GO:0000166	nucleotide binding	Molecular Function	IEA
GO:0005524	ATP binding	Molecular Function	IEA
GO:0004872	receptor activity	Molecular Function	IEA
GO:0004714	transmembrane receptor protein tyrosine kinase activity	Molecular Function	TAS (7685902)
GO:0016740	transferase activity	Molecular Function	IEA
GO:0006468	protein amino acid phosphorylation	Biological Process	TAS (7685902)
GO:0007165	signal transduction	Biological Process	TAS (7685902)
GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	Biological Process	IEA

Other Database Cross Links

NCBI Entrez Gene:

HGNC:

Ensembl:

ENSG00000062524

MIM:

HPRD:

HuGE Navigator:

dbSNP:

GeneCard:

AceView: