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Gene Information
Gene ID:4064
Symbol:CD180
Full Name:CD180 molecule
Alias:LY64|Ly78|MGC126233|MGC126234|RP105
Organism:Homo sapiens (Human)
Chromosome:5
Genetic Location:5q12
Physical Location:66513871-66528367 on NC_000005.8, complement
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Linkage Dataset
MarkerLODP valueLocation (bp)
D5S647  66282906
Region:66282906-76193808
Phenotype:Alcoholism phenotype along with age, gender, and P300 or constraint
Name:15211641
Method:Linkage
Publication:Hill et al. Am J Med Genet B Neuropsychiatr Genet. (2004) A genome wide search for alcoholism susceptibility genes. PubMed
Summary:A total of 360 markers for 22 autosomes were spaced at an average distance of 9.4cMand genotyping performed for 330 members of these multiplex families. Extensive clinical data, personality variation, and event-related potential characteristics were available for reducing heterogeneity and detecting robust linkage signals. Multipoint linkage analysis using different analytic strategies give strong support for loci on chromosomes 1, 2, 6, 7, 10, 12, 14, 16, and 17. Thirty five markers with LOD score >2.0 at baseline using the binary alcoholism phenotype along with age, gender, and P300 or constraint (Table III). Here we listed the genes between two near markers or genes near a separate marker (within 2Mb).
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_005582.2NP_005573.2NC_000005.8 range: 66513871..66528367, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005886plasma membraneCellular ComponentIEA
GO:0016021integral to membraneCellular ComponentIEA
GO:0004872receptor activityMolecular FunctionIEA
GO:0005515protein bindingMolecular FunctionTAS (8975706)
GO:0006954inflammatory responseBiological ProcessIEA
GO:0045087innate immune responseBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:4064
HGNC:6726
Ensembl:ENSG00000134061
MIM:602226
HPRD:03749
HuGE Navigator:4064
dbSNP:CD180
GeneCard:CD180
AceView:CD180