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Gene Information
Gene ID:4087
Symbol:SMAD2
Full Name:SMAD family member 2
Alias:JV18|JV18-1|MADH2|MADR2|MGC22139|MGC34440|hMAD-2|hSMAD2
Organism:Homo sapiens (Human)
Chromosome:18
Genetic Location:18q21.1
Physical Location:43613463-43711509 on NC_000018.8, complement
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:SMAD2
Dataset Information
Name:Literature Search
Method:Literature search
Summary:We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_001003652.2NP_001003652.1NC_000018.8 range: 43613463..43711509, complement
NM_005901.4NP_005892.1NC_000018.8 range: 43613463..43711509, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005829cytosolCellular ComponentEXP (9311995|9865696|11100470)
GO:0005737cytoplasmCellular ComponentIEA
GO:0005667transcription factor complexCellular ComponentISS
GO:0005654nucleoplasmCellular ComponentEXP (10549282)
GO:0005634nucleusCellular ComponentIEA
GO:0005622intracellularCellular ComponentIEA
GO:0003700transcription factor activityMolecular FunctionIEA
GO:0003690double-stranded DNA bindingMolecular FunctionISS
GO:0016563transcription activator activityMolecular FunctionISS
GO:0008134transcription factor bindingMolecular FunctionISS
GO:0008134transcription factor bindingMolecular FunctionIPI (9702198)
GO:0045892negative regulation of transcription, DNA-dependentBiological ProcessIMP (14555988)
GO:0045944positive regulation of transcription from RNA polymerase II promoterBiological ProcessISS
GO:0048340paraxial mesoderm morphogenesisBiological ProcessISS
GO:0001707mesoderm formationBiological ProcessISS
GO:0045165cell fate commitmentBiological ProcessISS
GO:0017015regulation of transforming growth factor beta receptor signaling pathwayBiological ProcessIMP (14555988)
GO:0009952anterior/posterior pattern formationBiological ProcessISS
GO:0007242intracellular signaling cascadeBiological ProcessISS
GO:0006350transcriptionBiological ProcessIEA
GO:0051098regulation of bindingBiological ProcessISS
Other Database Cross Links
NCBI Entrez Gene:4087
HGNC:6768
Ensembl:ENSG00000175387
MIM:601366
HPRD:03221
HuGE Navigator:4087
dbSNP:SMAD2
GeneCard:SMAD2
AceView:SMAD2