ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

SMAD2

Full Name:

SMAD family member 2

Alias:

JV18|JV18-1|MADH2|MADR2|MGC22139|MGC34440|hMAD-2|hSMAD2

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

18q21.1

Physical Location:

43613463-43711509 on NC_000018.8, complement

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

SMAD2

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005829	cytosol	Cellular Component	EXP (9311995\|9865696\|11100470)
GO:0005737	cytoplasm	Cellular Component	IEA
GO:0005667	transcription factor complex	Cellular Component	ISS
GO:0005654	nucleoplasm	Cellular Component	EXP (10549282)
GO:0005634	nucleus	Cellular Component	IEA
GO:0005622	intracellular	Cellular Component	IEA
GO:0003700	transcription factor activity	Molecular Function	IEA
GO:0003690	double-stranded DNA binding	Molecular Function	ISS
GO:0016563	transcription activator activity	Molecular Function	ISS
GO:0008134	transcription factor binding	Molecular Function	ISS
GO:0008134	transcription factor binding	Molecular Function	IPI (9702198)
GO:0045892	negative regulation of transcription, DNA-dependent	Biological Process	IMP (14555988)
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	Biological Process	ISS
GO:0048340	paraxial mesoderm morphogenesis	Biological Process	ISS
GO:0001707	mesoderm formation	Biological Process	ISS
GO:0045165	cell fate commitment	Biological Process	ISS
GO:0017015	regulation of transforming growth factor beta receptor signaling pathway	Biological Process	IMP (14555988)
GO:0009952	anterior/posterior pattern formation	Biological Process	ISS
GO:0007242	intracellular signaling cascade	Biological Process	ISS
GO:0006350	transcription	Biological Process	IEA
GO:0051098	regulation of binding	Biological Process	ISS