ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

MAP4

Full Name:

microtubule-associated protein 4

Alias:

DKFZp779A1753|MGC8617

Organism:

Homo sapiens (Human)

Chromosome:

Genetic Location:

3p21

Physical Location:

47867188-48105714 on NC_000003.10, complement

Gene Type:

protein-coding

Orthologs:

This gene has Mouse: 17758 ortholog(s) in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:		M64571
Fold Change:		-1.4, -1.5
Note:		Differential expression on the oligonucleotide array (two fold changes are from two case groups)

Dataset Information

Name:		11141048
Method:		Microarray
Tissue:		Frontal cortex
Phenotype:		Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:		Lewohl et al. Alcohol Clin Exp Res. (2000) Gene expression in human alcoholism: microarray analysis of frontal cortex. PubMed
Summary:		RNA was extracted from postmortem samples of superior frontal cortex of alcoholics and nonalcoholics. Relative levels of RNA were determined by array techniques. This study used both cDNA and oligonucleotide microarrays to provide coverage of a large number of genes and to allow cross-validation for those genes represented on both types of arrays. Expression levels were determined for over 4000 genes and 163 of these were found to differ by 40% or more between alcoholics and nonalcoholics.

Gene Refseq Sequence Annotation

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005874	microtubule	Cellular Component	IEA
GO:0005875	microtubule associated complex	Cellular Component	TAS (1905296)
GO:0005198	structural molecule activity	Molecular Function	TAS (1905296)
GO:0007026	negative regulation of microtubule depolymerization	Biological Process	IEA