ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

MC4R

Full Name:

melanocortin 4 receptor

Alias:

MGC126851|MGC138197

Organism:

Homo sapiens (Human)

Chromosome:

18

Genetic Location:

18q22

Physical Location:

56189543-56190980 on NC_000018.8, complement

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

MC4R

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_005912.2	NP_005903.2	NC_000018.8 range: 56189543..56190980, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005886	plasma membrane	Cellular Component	TAS (10585465)
GO:0016021	integral to membrane	Cellular Component	TAS (8392067)
GO:0001584	rhodopsin-like receptor activity	Molecular Function	IEA
GO:0004872	receptor activity	Molecular Function	IEA
GO:0004977	melanocortin receptor activity	Molecular Function	TAS (8794897)
GO:0007631	feeding behavior	Biological Process	TAS (9771698)
GO:0007188	G-protein signaling, coupled to cAMP nucleotide second messenger	Biological Process	TAS (8794897)
GO:0007186	G-protein coupled receptor protein signaling pathway	Biological Process	IEA
GO:0007165	signal transduction	Biological Process	IEA
GO:0045780	positive regulation of bone resorption	Biological Process	IMP (16614075)

Other Database Cross Links

NCBI Entrez Gene:

HGNC:

Ensembl:

ENSG00000166603

MIM:

HPRD:

HuGE Navigator:

dbSNP:

GeneCard:

AceView: