| Gene Information |
| Gene ID: | | 4185 |
| Symbol: | | ADAM11 |
| Full Name: | | ADAM metallopeptidase domain 11 |
| Alias: | | MDC |
| Organism: | | Homo sapiens (Human) |
| Chromosome: | | 17 |
| Genetic Location: | | 17q21.3 |
| Physical Location: | | 40192093-40214739 on NC_000017.9 |
| Gene Type: | | protein-coding |
| Orthologs: | | This gene has no orthologs in other dataset(s). |
|
| Gene in Ethanol Study Datasets |
| Gene Information | | Original ID | No. of Publications | Phenotype | |
| ADAM11 | 1 | Alcoholism | | ADAM11 | 1 | Alcohol-Related Disorders |
| | HuGE Navigator Dataset | | Name: | | HuGE Navigator | | Method: | | Literature data mining | | Publication: | | Wei Yu, Melinda Clyne, Anja Wulf, Ajay Yesupriya, Marta Gwinn and Muin J. Khoury. Phenopedia. HuGE Navigator. Available at: http://www.hugenavigator.net/HuGENavigator/startPagePhenoPedia.do. Accessed [Jun. 10, 2008]. | | Summary: | | HuGE Navigator Phenopedia provides a disease-centered view of genetic association studies summarized in the online Human Genome Epidemiology (HuGE) encyclopedia. We extracted genes associated to 9 Alcohol-related diseases (Alcohol Amnestic Disorder; Alcohol Withdrawal Delirium; Alcohol Withdrawal Seizures; Alcohol-Induced Disorders; Alcohol-Induced Disorders, Nervous System; Alcohol-Related Disorders; Alcoholic Intoxication; Alcoholic Neuropathy; Alcoholism) from HuGE Navigator Phenopedia. |
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|
| Gene Refseq Sequence Annotation |
|
| Gene Ontology (GO) Annotation |
| GO ID | GO Term | Category | Evidence (PubMed) | |
| GO:0005886 | plasma membrane | Cellular Component | TAS (9693107) | |
| GO:0016021 | integral to membrane | Cellular Component | IEA | |
| GO:0004222 | metalloendopeptidase activity | Molecular Function | IEA | |
| GO:0005178 | integrin binding | Molecular Function | TAS (9693107) | |
| GO:0008270 | zinc ion binding | Molecular Function | IEA | |
| GO:0006508 | proteolysis | Biological Process | IEA | |
| GO:0007229 | integrin-mediated signaling pathway | Biological Process | TAS (8252040) | |
|
| Other Database Cross Links |
| NCBI Entrez Gene: | | 4185 |
| HGNC: | | 189 |
| Ensembl: | | ENSG00000073670 |
| MIM: | | 155120 |
| HPRD: | | 01114 |
| HuGE Navigator: | | 4185 |
| dbSNP: | | ADAM11 |
| GeneCard: | | ADAM11 |
| AceView: | | ADAM11 |
