Logo
Home Search BLAST Integration Document Link Support Citation

Gene Information
Gene ID:4193
Symbol:MDM2
Full Name:Mdm2 p53 binding protein homolog (mouse)
Alias:HDMX|MGC71221|hdm2
Organism:Homo sapiens (Human)
Chromosome:12
Genetic Location:12q14.3-q15
Physical Location:67488246-67520480 on NC_000012.10
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:MDM2
Dataset Information
Name:Literature Search
Method:Literature search
Summary:We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_002392.2NP_002383.2NC_000012.10 range: 67488246..67520480
NM_006878.2NP_006869.3NC_000012.10 range: 67488246..67520480
NM_006879.2NP_006870.3NC_000012.10 range: 67488246..67520480
NM_006881.2NP_006872.3NC_000012.10 range: 67488246..67520480
NM_006882.2NP_006873.3NC_000012.10 range: 67488246..67520480
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005730nucleolusCellular ComponentIDA (10707090)
GO:0005829cytosolCellular ComponentEXP (11715018)
GO:0005737cytoplasmCellular ComponentIEA
GO:0005654nucleoplasmCellular ComponentIDA (10707090|12915590)
GO:0005654nucleoplasmCellular ComponentEXP (11331603)
GO:0005634nucleusCellular ComponentIEA
GO:0005626insoluble fractionCellular ComponentIDA (12915590)
GO:0005622intracellularCellular ComponentIEA
GO:0019899enzyme bindingMolecular FunctionIPI (15577914)
GO:0008270zinc ion bindingMolecular FunctionIEA
GO:0017163negative regulator of basal transcription activityMolecular FunctionISS
GO:0016874ligase activityMolecular FunctionIEA
GO:0008270zinc ion bindingMolecular FunctionIDA (10722742)
GO:0046872metal ion bindingMolecular FunctionIEA
GO:0005515protein bindingMolecular FunctionIEA
GO:0004842ubiquitin-protein ligase activityMolecular FunctionIDA (9450543)
GO:0042802identical protein bindingMolecular FunctionIPI (17936559)
GO:0017163negative regulator of basal transcription activityMolecular FunctionIDA (9271120)
GO:0042176regulation of protein catabolic processBiological ProcessIDA (9153395)
GO:0016567protein ubiquitinationBiological ProcessIDA (9450543)
GO:0008285negative regulation of cell proliferationBiological ProcessTAS (7791904)
GO:0006461protein complex assemblyBiological ProcessIDA (10608892|12915590)
GO:0000122negative regulation of transcription from RNA polymerase II promoterBiological ProcessISS
GO:0000122negative regulation of transcription from RNA polymerase II promoterBiological ProcessIDA (9271120)
Other Database Cross Links
NCBI Entrez Gene:4193
HGNC:6973
Ensembl:ENSG00000135679
MIM:164785
HPRD:01272
HuGE Navigator:4193
dbSNP:MDM2
GeneCard:MDM2
AceView:MDM2