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Gene Information
Gene ID:4221
Symbol:MEN1
Full Name:multiple endocrine neoplasia I
Alias:MEAI|SCG2
Organism:Homo sapiens (Human)
Chromosome:11
Genetic Location:11q13
Physical Location:64327563-64335341 on NC_000011.8, complement
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:MEN1
Dataset Information
Name:Literature Search
Method:Literature search
Summary:We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_000244.2NP_000235.2NC_000011.8 range: 64327563..64335341, complement
NM_130799.1NP_570711.1NC_000011.8 range: 64327563..64335341, complement
NM_130800.1NP_570712.1NC_000011.8 range: 64327563..64335341, complement
NM_130801.1NP_570713.1NC_000011.8 range: 64327563..64335341, complement
NM_130802.1NP_570714.1NC_000011.8 range: 64327563..64335341, complement
NM_130803.1NP_570715.1NC_000011.8 range: 64327563..64335341, complement
NM_130804.1NP_570716.1NC_000011.8 range: 64327563..64335341, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005634nucleusCellular ComponentIDA (9465067|14508515|15199122)
GO:0005634nucleusCellular ComponentIEA
GO:0005737cytoplasmCellular ComponentIDA (11500056)
GO:0005829cytosolCellular ComponentIDA (14508515)
GO:0000785chromatinCellular ComponentIDA (12874027)
GO:0035097histone methyltransferase complexCellular ComponentIPI (14992727)
GO:0016363nuclear matrixCellular ComponentIDA (12874027)
GO:0032154cleavage furrowCellular ComponentIDA (14508515)
GO:0005625soluble fractionCellular ComponentIDA (12874027)
GO:0018024histone-lysine N-methyltransferase activityMolecular FunctionIDA (14992727)
GO:0005515protein bindingMolecular FunctionIPI (17353931)
GO:0003690double-stranded DNA bindingMolecular FunctionIDA (15331604)
GO:0047485protein N-terminus bindingMolecular FunctionIPI (11526476)
GO:0046332SMAD bindingMolecular FunctionIPI (11274402)
GO:0000400four-way junction DNA bindingMolecular FunctionIDA (15331604)
GO:0000403Y-form DNA bindingMolecular FunctionIDA (15331604)
GO:0043433negative regulation of transcription factor activityBiological ProcessIDA (11526476|12226747)
GO:0045668negative regulation of osteoblast differentiationBiological ProcessIGI (15563473)
GO:0045736negative regulation of cyclin-dependent protein kinase activityBiological ProcessIMP (15640349)
GO:0046329negative regulation of JNK cascadeBiological ProcessIDA (12226747)
GO:0000122negative regulation of transcription from RNA polymerase II promoterBiological ProcessIDA (9989505)
GO:0030511positive regulation of transforming growth factor beta receptor signaling pathwayBiological ProcessIMP (11274402)
GO:0016481negative regulation of transcriptionBiological ProcessIDA (12226747)
GO:0010332response to gamma radiationBiological ProcessIDA (12874027)
GO:0009411response to UVBiological ProcessIDA (16690369)
GO:0008285negative regulation of cell proliferationBiological ProcessIDA (15331604)
GO:0006281DNA repairBiological ProcessNAS (12874027)
GO:0002076osteoblast developmentBiological ProcessIGI (15563473)
GO:0001933negative regulation of protein amino acid phosphorylationBiological ProcessIDA (12226747)
GO:0000165MAPKKK cascadeBiological ProcessIDA (12226747)
GO:0051974negative regulation of telomerase activityBiological ProcessIMP (12837246)
Other Database Cross Links
NCBI Entrez Gene:4221
HGNC:7010
Ensembl:ENSG00000133895
MIM:131100
HPRD:00564
HuGE Navigator:4221
dbSNP:MEN1
GeneCard:MEN1
AceView:MEN1