ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

MGMT

Full Name:

O-6-methylguanine-DNA methyltransferase

Organism:

Homo sapiens (Human)

Chromosome:

10

Genetic Location:

10q26

Physical Location:

131155455-131455357 on NC_000010.9

Gene Type:

protein-coding

Orthologs:

This gene has no orthologs in other dataset(s).

Gene in Ethanol Study Datasets

Gene Information

Original ID1:

MGMT

Dataset Information

Name:		Literature Search
Method:		Literature search
Summary:		We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_002412.2	NP_002403.1	NC_000010.9 range: 131155455..131455357

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	TAS (2188979)
GO:0005654	nucleoplasm	Cellular Component	EXP (8434121)
GO:0003677	DNA binding	Molecular Function	TAS (2188979)
GO:0016740	transferase activity	Molecular Function	IEA
GO:0009008	DNA-methyltransferase activity	Molecular Function	TAS (2405387)
GO:0008270	zinc ion binding	Molecular Function	IEA
GO:0046872	metal ion binding	Molecular Function	IEA
GO:0003908	methylated-DNA-[protein]-cysteine S-methyltransferase activity	Molecular Function	IEA
GO:0003908	methylated-DNA-[protein]-cysteine S-methyltransferase activity	Molecular Function	EXP (8434121)
GO:0006281	DNA repair	Biological Process	IEA
GO:0006266	DNA ligation	Biological Process	TAS (2188979)

Other Database Cross Links

NCBI Entrez Gene:

HGNC:

Ensembl:

ENSG00000170430

MIM:

HPRD:

HuGE Navigator:

dbSNP:

GeneCard:

AceView: