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Gene Information
Gene ID:43
Symbol:ACHE
Full Name:acetylcholinesterase (Yt blood group)
Alias:ARACHE|N-ACHE|YT
Organism:Homo sapiens (Human)
Chromosome:7
Genetic Location:7q22
Physical Location:100325550-100331476 on NC_000007.12, complement
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:ACHE
Dataset Information
Name:Literature Search
Method:Literature search
Summary:We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_000665.3NP_000656.1NC_000007.12 range: 100325550..100331476, complement
NM_015831.2NP_056646.1NC_000007.12 range: 100325550..100331476, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0031225anchored to membraneCellular ComponentIEA
GO:0030054cell junctionCellular ComponentIEA
GO:0045202synapseCellular ComponentIDA (8460160)
GO:0005886plasma membraneCellular ComponentIEA
GO:0005794Golgi apparatusCellular ComponentIDA (15454088)
GO:0005605basal laminaCellular ComponentNAS (16289501)
GO:0005576extracellular regionCellular ComponentTAS (11283752)
GO:0048471perinuclear region of cytoplasmCellular ComponentIDA (14766237)
GO:0005518collagen bindingMolecular FunctionIDA (12524166)
GO:0017171serine hydrolase activityMolecular FunctionIDA (3954986)
GO:0042166acetylcholine bindingMolecular FunctionNAS (1517212)
GO:0042803protein homodimerization activityMolecular FunctionNAS (1517212)
GO:0001540beta-amyloid bindingMolecular FunctionTAS (11283752)
GO:0043237laminin-1 bindingMolecular FunctionIDA (12524166)
GO:0003990acetylcholinesterase activityMolecular FunctionIEA
GO:0003990acetylcholinesterase activityMolecular FunctionIMP (1517212)
GO:0004104cholinesterase activityMolecular FunctionIDA (1517212)
GO:0004104cholinesterase activityMolecular FunctionIEA
GO:0016787hydrolase activityMolecular FunctionIEA
GO:0032223negative regulation of synaptic transmission, cholinergicBiological ProcessIC (1517212)
GO:0042982amyloid precursor protein metabolic processBiological ProcessTAS (12769797)
GO:0001507acetylcholine catabolic process in synaptic cleftBiological ProcessNAS (1517212)
GO:0009611response to woundingBiological ProcessTAS (11283752)
GO:0008283cell proliferationBiological ProcessTAS (11283752)
GO:0007517muscle developmentBiological ProcessTAS (11283752)
GO:0007416synaptogenesisBiological ProcessTAS (11283752)
GO:0007155cell adhesionBiological ProcessTAS (11283752)
GO:0006260DNA replicationBiological ProcessTAS (11283752)
GO:0002076osteoblast developmentBiological ProcessIEP (15454088)
GO:0050714positive regulation of protein secretionBiological ProcessTAS (11283752)
Other Database Cross Links
NCBI Entrez Gene:43
HGNC:108
Ensembl:ENSG00000087085
MIM:100740
HPRD:00010
HuGE Navigator:43
dbSNP:ACHE
GeneCard:ACHE
AceView:ACHE